캄펜 C화학적 특성, 용도, 생산
화학적 성질
Camphene is a colorless to white crystalline
solid, Camphor, or turpentine odor. It may be shipped as a
liquid. Freezing/Melting point 5 50C.
출처
Reported found in carrot, dill, fennel, marjoram, nutmeg, parsley, pepper, tarragon and thyme.
용도
Camphene is used in the preparation of fragrances and as a food additive for flavoring.
제조 방법
From pinene by catalytic isomerization or from bornyl chloride by heating with alkali in the presence of abietenesulfonic acid.
정의
ChEBI: A monoterpene with a bicyclic skeleton that is bicyclo[2.2.1]heptane substituted by geminal methyl groups at position 2 and a methylidene group at position 3. It is a widespread natural product found in many essential oils.
일반 설명
A colorless to white crystalline solid with an insipid camphor-like odor. Dust and crystals are irritants to the eyes, nose and throat. Emits flammable vapors when heated. Emits acrid smoke and irritating fumes at high temperature. Used for the manufacture of synthetic camphor.
반응 프로필
Camphene may react vigorously with strong oxidizing agents. May react exothermically with reducing agents to release hydrogen gas.
위험도
Toxic by ingestion.
건강위험
Inhalation causes irritation of nose and throat. Contact with eyes or skin causes irritation.
Pharmacology
Oral administration of camphene (260 mmols/kg) to rats increased bile flow by 50%
4 hr after administration (M?rsdorf, 1966). Development of atheromatosis of the aorta in rabbits
fed 1 g cholesterol/day for 3 months was considerably inhibited by simultaneous administration
of a mixture of terpenes including camphene, injected sc in a dose of 1 ml every other day for
6 wk and then given orally in doses of 2 ml/day (Benk?, Macher, Szarvas & Tiboldi, 1961). The
effect of 1 g cholesterol/day for 8 wk in the diet of rabbits in increasing the number and volume
of mast cells in the aortic adventitia and increasing the total lipid content of the aortic wall was
slightly enhanced by the simultaneous addition of 11 g camphene/day (Lesznyak, Benko, Szabo
& Muller, 1972). This camphene treatment also decreased the lipid accumulation in the liver, but
had no effect on the cholesterol-induced atheromatosis of the aorta (Benko, Szabo, Muller & Lesznyak,
1972).
Anticancer Research
This was tested against melanoma cells in a syngeneic model, and there was promisingantitumor activity (Ma et al. 2016).
Safety Profile
Mutation data reported.
Combustible; yields flammable vapors when
heated and can react with oxidizing
materials. To fight fire, use water spray,
foam, fog, CO2. When heated to
decomposition it emits acrid smoke and
irritating fumes.
잠재적 노출
Camphene is used to manufacture synthetic camphor; for making moth-proofing and in the cosmetics, perfume, and food flavoring industries.
운송 방법
UN1325 Flammable solids, organic, n.o.s.,
Hazard Class: 4.1; Labels: 4.1-Flammable solid. UN2319
Terpene hydrocarbons, n.o.s., Hazard Class: 3; Labels: 3-
Flammable liquid
비 호환성
Forms explosive mixture with air.
Emulsions in xylene may violently decompose on contact
with iron or aluminum above 70C. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may
cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Contact
with reducing agents may cause exothermic reaction,
releasing flammable hydrogen gas
폐기물 처리
Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal,
state, and local environmental regulations must be
observed.
캄펜 준비 용품 및 원자재
원자재
준비 용품
