42-(Dimethylphosphinate)rapamycin suppliers
42-(Dimethylphosphinate)rapamycin
- CAS:
- 572924-54-0
- MF:
- C53H84NO14P
- MW:
- 990.21
Suppliers by country/region
Company Type
Properties
- Melting point:
- 95-98°C
- Boiling point:
- 996.2±75.0 °C(Predicted)
- Density
- 1.18±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 10.40±0.70(Predicted)
- color
- Off-White to Pale Yellow
- Stability:
- Hygroscopic
Safety Information
- Symbol(GHS)
GHS08,GHS09
- Signal word
- Warning
- Hazard statements
- H373-H400
- Precautionary statements
- P273-P391-P501-P260-P314-P501
Use
Ridaforolimus is a semisynthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a dimethylphosphinate moiety. Like all tacrolimus analogues, ridaforolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing its interaction with target proteins. Ridaforolimus is extensively cited in the literature with over 70 citations.An immunosupressant and is currently being investigated for use in cancer treatments. Ridaforolimus may act as a regulator of protein synthesis, cell proliferation, cell cycle progression and cell survival. Ridaforolimus, was formerly known as Deforolimus.
87 supplier list of "42-(Dimethylphosphinate)rapamycin"
- Product Name:Ridaforolimus
- Products Intro:Purity: As coa | Package: As request | CustNote: 572924-54-0
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Ridaforolimus
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
$7.00/ 1KG
- Product Name: Ridaforolimus
- Products Intro:Purity: 99% | Package: 1KG;7USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
- Product Name:42-(Dimethylphosphinate)rapamycin
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Daily Chemicals
- Product Name:Deforolimus (AP23573)
- Products Intro:Purity: 0.99 | Package: 25G;1G
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Bredereck's Reagent,Salicylic Acid,Amino Acids,Bipyridine Derivatives,Phenanthroline Derivatives
- Product Name:42-(Dimethylphosphinate)rapamycin
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chlorogenic acid,Tea polyphenol,Acacetin,Gentiopicroside,Jatrorrhizine
- Product Name:42-(Dimethylphosphinate)rapamycin
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Ridaforolimus
- Products Intro:Purity: >95% by HPLC | CustNote: BOC Sciences also provides custom synthesis services for Ridaforolimus.
- Company Type: Reagent
- Country/Region: UNITED STATES
- Product Name:Deforolimus
- Products Intro:Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Hot sales
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Ridaforolimus
- Products Intro:Purity: 99% | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms