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ChemicalBook >> CAS DataBase List >>Palbociclib

Palbociclib suppliers

Palbociclib

CAS:
571190-30-2
MF:
C24H29N7O2
MW:
447.53

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Properties

Melting point:
200 ºC
Boiling point:
711.5±70.0 °C(Predicted)
Density 
1.313±0.06 g/cm3(Predicted)
storage temp. 
room temp
solubility 
Soluble in DMSO (up to 2 mg/ml with warming)
pka
8.66±0.10(Predicted)
form 
powder
color 
white to beige
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS) 
GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS09
Signal word 
Warning
Hazard statements 
H341-H361f-H373-H411
Precautionary statements 
P201-P202-P260-P273-P280-P308+P313

Use

Palbociclib (Ibrane(R), Pfizer), a selective CDK4 and CDK6 inhibitor, received accelerated approval from FDA in 2015 for women with estrogen receptor-positive and HER2-negative breast cancer in combination with letrozole.

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