DL-2-Hydroxybutyric Acid manufacturers and suppliers

DL-2-Hydroxybutyric Acid suppliers

DL-2-Hydroxybutyric Acid

CAS:: 600-15-7

MF:: C4H8O3

MW:: 104.1

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Properties

Melting point:: 44 °C

Boiling point:: 260 °C

Density: 1.1250

refractive index: 1.4298 (589.3 nm 20℃)

storage temp.: Refrigerator

solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

form: Solid

pka: pK1:3.65 (30°C)

color: White to Off-White

Merck: 14,4816

Safety Information

Symbol(GHS): GHS05,GHS07

Signal word: Danger

Hazard statements: H315-H318-H335

Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes: Xi

Risk Statements: 36/37/38-41-37/38

Safety Statements: 26-36/37/39-39

HS Code: 2918199890

Use

2-Hydroxybutyric acid (or alpha - hydroxy butyrate) is a hydroxy butyric acid with the hydroxyl group on the carbon adjacent to the carboxyl. It is a chiral compound having two enantiomers, D-2- hydroxybutyric acid and L-2-hydroxybutyric acid. 2-Hydroxy butyrate, the conjugate base of 2-hydroxy butyric acid, is produced in mammalian tissues (principally hepatic) that catabolize L-threonine or synthesize glutathione. Oxidative stress or detoxification demands can dramatically increase the rate of hepatic glutathione synthesis. Under such metabolic stress conditions, supplies of L-cysteine for glutathione synthesis become limiting, so homocysteine is diverted from the transmethylation pathway forming methionine into the transsulfuration pathway forming cystathionine. 2-Hydroxybutyrate is released as a byproduct when cystathionine is cleaved to cysteine that is incorporated into glutathione. Chronic shifts in the rate of glutathione synthesis may be reflected by urinary excretion of 2-hydroxybutyrate.

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