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ChemicalBook >> CAS DataBase List >>Meprobamate

Meprobamate suppliers

Meprobamate

CAS:
57-53-4
MF:
C9H18N2O4
MW:
218.25

Company Type

Properties

Melting point:
97-100°C
Boiling point:
358.93°C (rough estimate)
Density 
1.2004 (rough estimate)
refractive index 
1.4480 (estimate)
Flash point:
11 °C
storage temp. 
2-8°C
solubility 
DMF: 50 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 30 mg/ml; Ethanol: 25 mg/ml
pka
13.09±0.50(Predicted)
Water Solubility 
6.2g/L(25 ºC)
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.

Safety Information

Symbol(GHS) 
GHS hazard pictograms
GHS07
Signal word 
Warning
Hazard statements 
H302
Precautionary statements 
P301+P312+P330
Hazard Codes 
Xn,T,F
Risk Statements 
22-39/23/24/25-23/24/25-11
Safety Statements 
7-16-36/37-45
RIDADR 
UN 1230 3/PG 2
WGK Germany 
3
RTECS 
TZ0175000
HS Code 
2924110000
Toxicity
LD50 i.p. in mice: 800 mg/kg (Berger)

Use

Meprobamate, a bis-carbamate ester, was introduced in 1955 for the treatment of anxiety and was subsequently used as a sedative-hypnotic drug. Psychological and physical dependence can occur and abuse has been reported. Meprobamate is controlled under Schedule IV of the 1971 Convention on Psychotropic Substances. (Reference: (UNCPS4) United Nations Convention on Psychotropic Substances (IV), , , 1971)

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