SB 202190 suppliers
SB 202190
- CAS:
- 152121-30-7
- MF:
- C20H14FN3O
- MW:
- 331.34
Suppliers by country/region
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Properties
- Melting point:
- 240-243℃
- Boiling point:
- 565.7±50.0 °C(Predicted)
- Density
- 1.31
- RTECS
- SL4584000
- storage temp.
- 2-8°C
- solubility
- DMSO: 30 mg/mL, soluble
- pka
- 9.14±0.15(Predicted)
- form
- Pale yellow solid
- color
- pale yellow
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
- InChIKey
- QHKYPYXTTXKZST-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P280a-P304+P340-P305+P351+P338-P405-P501a
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37
- WGK Germany
- 3
- HS Code
- 29333990
Use
SB 202190 is a DFG inhibitor used in the treatment of colorectal cancer. It is a highly selective, potent inhibitor of p38 MAP kinase. SB-202190 is able to promote proliferation of C6 cells in lower c oncentration but induced apoptosis in higher levels. Studies show that SB202190 can protect neural function from ischemia/reperfusion injury and regulate the activation of Bcl-2 and Bax protein after ischemia/reperfusion in rat.
165 supplier list of "SB 202190"
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