Triazolam suppliers
Triazolam
- CAS:
- 28911-01-5
- MF:
- C17H12Cl2N4
- MW:
- 343.21
Company Type
Properties
- Melting point:
- 209-212°C
- Boiling point:
- 499.51°C (rough estimate)
- Density
- 1.2835 (rough estimate)
- refractive index
- 1.6300 (estimate)
- Flash point:
- 11 °C
- storage temp.
- 2-8°C
- solubility
- DMF: 30 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
- form
- A crystalline solid
- pka
- pKa 1.52(H2O) (Uncertain);6.5(H2O) (Uncertain)
- Water Solubility
- 30mg/L(ambient temperature)
Safety Information
- Symbol(GHS)
GHS02,GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H225-H301+H311+H331-H370
- Precautionary statements
- P210-P260-P280-P301+P310-P311
- Hazard Codes
- F,T
- Risk Statements
- 11-23/24/25-36/38-39/23/24/25
- Safety Statements
- 22-24/25-26-36-45-36/37-16-7
- RIDADR
- 3249
- WGK Germany
- 2
- RTECS
- XZ5472500
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 2933910000
- Toxicity
- LD50 in mice, rats (mg/kg): >100, >5000 orally (Pharm. Weekblad.)
Use
Triazolam is usually used for short-term treatment of acute insomnia and circadian rhythm sleep disorders, including jet lag. It is an ideal benzodiazepine for this use because of its fast onset of action and short half-life. It puts a person to sleep for about 1.5 hours, allowing its user to avoid morning drowsiness. Triazolam is also sometimes used as an adjuvant in medical procedures requiring anesthesia or to reduce anxiety during brief events, such as MRI scans and nonsurgical dental procedures. Triazolam is ineffective in maintaining sleep, however, due to its short half-life, with quazepam showing superiority.
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