2-[[(1R)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-4h-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid
![2-[[(1R)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-4h-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid price.](/CAS2/GIF/1173900-33-8.gif)
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- $32 - $9606
- Product name: 2-[[(1R)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-4h-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid
- CAS: 1173900-33-8
- MF: C22H24N4O4
- MW: 408.45
- EINECS:-0
- MDL Number:MFCD16659062
- Synonyms:2-[[(1R)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-4h-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid;AZD 6482;AZD6482(PI3-kinase β inhibitor);AZD-6482/AZD6482;AZD6482(r);(R)AZD64822-[[(1R)-1-[7-Methyl-2-(4-Morpholinyl)-4-oxo-4h-pyrido[1,2-a]pyriMidin-9-yl]ethyl]aMino]benzoic acid;KIN-193;2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid AZD 6482
31 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 50
- 1MG
- 10mg
- 25mg
- 50mg
- 100mg
- 10
- 1g
- ManufacturerAK Scientific
- Product number2243AH
- Product description2-[[(1R)-1-(7-Methyl-2-morpholin-4-yl-4-oxopyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoicacid
- Packaging1g
- Price$9606
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA560000
- Product descriptionAzd6482 98+%
- Packaging10mg
- Price$126
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA560000
- Product descriptionAzd6482 98+%
- Packaging50mg
- Price$422
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA560000
- Product descriptionAzd6482 98+%
- Packaging100mg
- Price$549
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000923
- Product description(R)-2-(1-(7-METHYL-2-MORPHOLINO-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-9-YL)ETHYLAMINO)BENZOIC ACID 95.00%
- Packaging1MG
- Price$148.05
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000923
- Product description(R)-2-(1-(7-METHYL-2-MORPHOLINO-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-9-YL)ETHYLAMINO)BENZOIC ACID 95.00%
- Packaging10MG
- Price$1006.58
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000923
- Product description(R)-2-(1-(7-METHYL-2-MORPHOLINO-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-9-YL)ETHYLAMINO)BENZOIC ACID 95.00%
- Packaging50MG
- Price$1734.23
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000923
- Product description(R)-2-(1-(7-METHYL-2-MORPHOLINO-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-9-YL)ETHYLAMINO)BENZOIC ACID 95.00%
- Packaging1G
- Price$8101.17
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5478
- Product descriptionAZD6482
- Packaging25mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60266
- Product descriptionAZD6482
- Packaging10mg
- Price$378
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2926
- Product descriptionAZD6482-KIN-193 99%
- Packaging5mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2926
- Product descriptionAZD6482-KIN-193 99%
- Packaging25mg
- Price$462
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA137652
- Product descriptionAZD 6482
- Packaging10mg
- Price$245
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA137652
- Product descriptionAZD 6482
- Packaging50mg
- Price$857.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15250
- Product descriptionAZD6482 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15250
- Product descriptionAZD6482 ≥98%
- Packaging5mg
- Price$131
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2243AH | 2-[[(1R)-1-(7-Methyl-2-morpholin-4-yl-4-oxopyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoicacid | 1g | $9606 | 2021-12-16 | Buy |
| Ambeed | A560000 | Azd6482 98+% | 10mg | $126 | 2021-12-16 | Buy |
| Ambeed | A560000 | Azd6482 98+% | 50mg | $422 | 2021-12-16 | Buy |
| Ambeed | A560000 | Azd6482 98+% | 100mg | $549 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000923 | (R)-2-(1-(7-METHYL-2-MORPHOLINO-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-9-YL)ETHYLAMINO)BENZOIC ACID 95.00% | 1MG | $148.05 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000923 | (R)-2-(1-(7-METHYL-2-MORPHOLINO-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-9-YL)ETHYLAMINO)BENZOIC ACID 95.00% | 10MG | $1006.58 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000923 | (R)-2-(1-(7-METHYL-2-MORPHOLINO-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-9-YL)ETHYLAMINO)BENZOIC ACID 95.00% | 50MG | $1734.23 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000923 | (R)-2-(1-(7-METHYL-2-MORPHOLINO-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-9-YL)ETHYLAMINO)BENZOIC ACID 95.00% | 1G | $8101.17 | 2021-12-16 | Buy |
| ApexBio Technology | A5478 | AZD6482 | 25mg | $360 | 2021-12-16 | Buy |
| Arctom | CFN60266 | AZD6482 | 10mg | $378 | 2021-12-16 | Buy |
| Axon Medchem | Axon2926 | AZD6482-KIN-193 99% | 5mg | $132 | 2021-12-16 | Buy |
| Axon Medchem | Axon2926 | AZD6482-KIN-193 99% | 25mg | $462 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA137652 | AZD 6482 | 10mg | $245 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA137652 | AZD 6482 | 50mg | $857.5 | 2021-12-16 | Buy |
| Cayman Chemical | 15250 | AZD6482 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 15250 | AZD6482 ≥98% | 5mg | $131 | 2024-03-01 | Buy |
Properties
Boiling point :635.5±65.0 °C(Predicted)
Density :1.36
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥20.4 mg/mL in DMSO; ≥6.36 mg/mL in EtOH
form :solid
pka :3.90±0.50(Predicted)
Density :1.36
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥20.4 mg/mL in DMSO; ≥6.36 mg/mL in EtOH
form :solid
pka :3.90±0.50(Predicted)
Safety Information
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Description
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3' hydroxyl position of PIs to produce the second messengers PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3. PI3Kα, β, and δ are class 1A enzymes composed of p110 and p85 subunits, whereas PI3Kγ is a class 1B PI3K composed of a p110 catalytic subunit and a p101 or p84 regulatory subunit. AZD6482 is a PI3K inhibitor that targets the β isoform more potently than PI3Kδ, PI3Kγ, or PI3Kα (IC50s = 0.69, 13.6, 47.8, and 136 nM, respectively). It displays 80-fold selectivity for PI3Kβ over PI3k-C2 and DNA-PK and more than 1,000-fold over other PI3K-related kinases. AZD6482 blocks Akt signaling and tumor growth in a large number of cancer cell lines, including those that are dependent on PI3Kβ activation or PTEN loss. AZD6482 (20 mg/kg, i.p.) suppresses the growth of PTEN-deficient xenograft tumors in mice. It also produces an anti-thrombotic effect in dogs without an increase in bleeding time or blood loss.More related product prices
4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]- 1217486-61-7 GSK2636771 ABT-199 MK-2206 2HCl BKM120 (NVP-BKM120, Buparlisib) BMS-794833 371942-69-7 356559-20-1 675576-98-4 R428 Tozasertib NVP-BVU 972 ARRY-424704, ARRY-704 Binimetinib ChlorotrimethylsilaneRelated product price
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Suppliers and manufacturers
career henan chemical co
![2-[[(1R)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-4h-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid](https://img.chemicalbook.com/ProductImageEN/2018-8/small/5c80356e-28ed-46e0-8e40-ef35d7b6a689.png)
Capot Chemical Co.,Ltd.
Biochempartner
Hubei Jusheng Technology Co.,Ltd.
Chongqing Chemdad Co., Ltd
Alchem Pharmtech,Inc.
CONIER CHEM AND PHARMA LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
$1.00 /1KG
2-[[(1R)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-4h-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid CAS:1173900-33-8
2-[[(1R)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-4h-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid CAS:1173900-33-8