12-EPI LEUKOTRIENE B4
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- $155 - $587
- Product name: 12-EPI LEUKOTRIENE B4
- CAS: 83709-73-3
- MF: C20H32O4
- MW: 336.47
- EINECS:
- MDL Number:MFCD00065829
- Synonyms:12-EPI LEUKOTRIENE B4;5S,12S-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENOIC ACID;(5S,6Z,8E,10E,12S,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid;12(S)-Leukotriene B4;VNYSSYRCGWBHLG-CBBLYLIKSA-N;6,8,10,14-Eicosatetraenoic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12S,14Z)-
6 prices
Selected condition：
Brand
- AHH
- Cayman Chemical
- TRC
Package
- 25μg
- 50μg
- 0.0001g
- 100μg
- ManufacturerAHH
- Product numberMT-11695
- Product description12-EpileukotrieneB4 97%
- Packaging0.0001g
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number20135
- Product description12-epi Leukotriene B4 ≥97%
- Packaging25μg
- Price$165
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20135
- Product description12-epi Leukotriene B4 ≥97%
- Packaging50μg
- Price$311
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20135
- Product description12-epi Leukotriene B4 ≥97%
- Packaging100μg
- Price$587
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberL330363
- Product description12-epiLeukotrieneB4
- Packaging25μg
- Price$155
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberL330363
- Product description12-epiLeukotrieneB4
- Packaging50μg
- Price$250
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-11695 | 12-EpileukotrieneB4 97% | 0.0001g | $410 | 2021-12-16 | Buy |
| Cayman Chemical | 20135 | 12-epi Leukotriene B4 ≥97% | 25μg | $165 | 2024-03-01 | Buy |
| Cayman Chemical | 20135 | 12-epi Leukotriene B4 ≥97% | 50μg | $311 | 2024-03-01 | Buy |
| Cayman Chemical | 20135 | 12-epi Leukotriene B4 ≥97% | 100μg | $587 | 2024-03-01 | Buy |
| TRC | L330363 | 12-epiLeukotrieneB4 | 25μg | $155 | 2021-12-16 | Buy |
| TRC | L330363 | 12-epiLeukotrieneB4 | 50μg | $250 | 2021-12-16 | Buy |
Properties
Boiling point :536.4±50.0 °C(Predicted)
Density :1.040±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C, protect from light
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
pka :4.66±0.10(Predicted)
Density :1.040±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C, protect from light
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
pka :4.66±0.10(Predicted)
Safety Information
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| Signal word: | Danger | ||||||||||||||||||||||
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Description
Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. The products of enzymatic origin, via Leukotriene A4 (LTA4) hydrolase, are stereospecifically 12(R). Non-enzymatic hydrolysis products are 50:50 mixtures at C-12, but are almost exclusively trans at C-6. Thus, the non-enzymatic hydrolysis product of LTA4 is 6-trans-12-epi LTB4. 12-epi LTB4 is an isomer which would not be expected to occur in either non-enzymatic hydrolysis products, or in the enzymatic products of LTA4 hydrolase. Compared to LTB4, 12-epi LTB4 has significantly reduced activity for the LTB4 receptor on human neutrophils (IC50 of 7.5 mM), and on guinea pig lung membranes with a (Ki of 4.7 mM). 12-epi LTB4 is an weak agonist at both the recombinant human BLT1 and BLT2 receptors, requiring approximately 10 mM for full activation of the receptor.More related product prices
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