4-[4-(1-methyl-1H-pyrazol-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-1H-imidazol-5-yl]-benzonitrile
![4-[4-(1-methyl-1H-pyrazol-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-1H-imidazol-5-yl]-benzonitrile price.](/CAS/20180703/GIF/1665195-94-7.gif)
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- $45 - $5450
- Product name: 4-[4-(1-methyl-1H-pyrazol-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-1H-imidazol-5-yl]-benzonitrile
- CAS: 1665195-94-7
- MF: C20H19N7
- MW: 357.41
- EINECS:
- MDL Number:MFCD28166490
- Synonyms:4-[4-(1-methyl-1H-pyrazol-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-1H-imidazol-5-yl]-benzonitrile;BAZ2-ICR;CPD1614;BAZ2ICR; BAZ2 ICR;Benzonitrile, 4-[4-(1-methyl-1H-pyrazol-4-yl)-1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-1H-imidazol-5-yl]-;BAZ2ICR,BAZ-2-ICR,BAZ2 ICR
25 prices
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Brand
- AK Scientific
- ApexBio Technology
- BroadPharm
- Cayman Chemical
- ChemScene
- DC Chemicals
- Tocris
- TRC
Package
- 50
- 1mg
- 5mg
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- ManufacturerAK Scientific
- Product number6030EB
- Product description4-[5-(1-Methylpyrazol-4-yl)-3-[2-(1-methylpyrazol-4-yl)ethyl]imidazol-4-yl]benzonitrile
- Packaging1mg
- Price$148
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6030EB
- Product description4-[5-(1-Methylpyrazol-4-yl)-3-[2-(1-methylpyrazol-4-yl)ethyl]imidazol-4-yl]benzonitrile
- Packaging5mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4915
- Product descriptionBAZ2-ICR
- Packaging5mg
- Price$174
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4915
- Product descriptionBAZ2-ICR
- Packaging10mg
- Price$275
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4915
- Product descriptionBAZ2-ICR
- Packaging25mg
- Price$624
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-25348
- Product descriptionBAZ2-ICR
- Packaging10mg
- Price$194
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-25348
- Product descriptionBAZ2-ICR
- Packaging25mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-25348
- Product descriptionBAZ2-ICR
- Packaging50mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17448
- Product descriptionBAZ2-ICR ≥98%
- Packaging1mg
- Price$45
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17448
- Product descriptionBAZ2-ICR ≥98%
- Packaging5mg
- Price$155
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17448
- Product descriptionBAZ2-ICR ≥98%
- Packaging10mg
- Price$241
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17448
- Product descriptionBAZ2-ICR ≥98%
- Packaging25mg
- Price$547
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0015282
- Product descriptionBAZ2-ICR >99.0%
- Packaging5mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0015282
- Product descriptionBAZ2-ICR >99.0%
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0015282
- Product descriptionBAZ2-ICR >99.0%
- Packaging25mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0015282
- Product descriptionBAZ2-ICR >99.0%
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 6030EB | 4-[5-(1-Methylpyrazol-4-yl)-3-[2-(1-methylpyrazol-4-yl)ethyl]imidazol-4-yl]benzonitrile | 1mg | $148 | 2021-12-16 | Buy |
| AK Scientific | 6030EB | 4-[5-(1-Methylpyrazol-4-yl)-3-[2-(1-methylpyrazol-4-yl)ethyl]imidazol-4-yl]benzonitrile | 5mg | $270 | 2021-12-16 | Buy |
| ApexBio Technology | B4915 | BAZ2-ICR | 5mg | $174 | 2021-12-16 | Buy |
| ApexBio Technology | B4915 | BAZ2-ICR | 10mg | $275 | 2021-12-16 | Buy |
| ApexBio Technology | B4915 | BAZ2-ICR | 25mg | $624 | 2021-12-16 | Buy |
| BroadPharm | BP-25348 | BAZ2-ICR | 10mg | $194 | 2021-12-16 | Buy |
| BroadPharm | BP-25348 | BAZ2-ICR | 25mg | $400 | 2021-12-16 | Buy |
| BroadPharm | BP-25348 | BAZ2-ICR | 50mg | $600 | 2021-12-16 | Buy |
| Cayman Chemical | 17448 | BAZ2-ICR ≥98% | 1mg | $45 | 2024-03-01 | Buy |
| Cayman Chemical | 17448 | BAZ2-ICR ≥98% | 5mg | $155 | 2024-03-01 | Buy |
| Cayman Chemical | 17448 | BAZ2-ICR ≥98% | 10mg | $241 | 2024-03-01 | Buy |
| Cayman Chemical | 17448 | BAZ2-ICR ≥98% | 25mg | $547 | 2024-03-01 | Buy |
| ChemScene | CS-0015282 | BAZ2-ICR >99.0% | 5mg | $100 | 2021-12-16 | Buy |
| ChemScene | CS-0015282 | BAZ2-ICR >99.0% | 10mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-0015282 | BAZ2-ICR >99.0% | 25mg | $250 | 2021-12-16 | Buy |
| ChemScene | CS-0015282 | BAZ2-ICR >99.0% | 50mg | $450 | 2021-12-16 | Buy |
Properties
Boiling point :632.8±55.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
solubility :DMSO:18.58(Max Conc. mg/mL);51.99(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);55.96(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.4(Max Conc. mM)
Ethanol:13.37(Max Conc. mg/mL);37.41(Max Conc. mM) form :A crystalline solid
pka :4.29±0.61(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
solubility :DMSO:18.58(Max Conc. mg/mL);51.99(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);55.96(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.4(Max Conc. mM)
Ethanol:13.37(Max Conc. mg/mL);37.41(Max Conc. mM) form :A crystalline solid
pka :4.29±0.61(Predicted)
Safety Information
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Description
BAZ2A/B are bromodomain-containing proteins whose biological function, while not yet confirmed, is believed to function similarly to ACF1, the Drosophila BAZ2B ortholog. ACF complexes play roles in establishing regular nucleosome spacing during chromatin assembly and influencing different remodeling outcomes at target loci. A rare allele of BAZ2B has been identified to be a predictor of Sudden Cardiac Death. BAZ2-ICR is a small molecule inhibitor of BAZ2A (Kd = 109 nM; IC50 = 130 nM) and BAZ2B (Kd = 170 nM; IC50 = 180 nM) bromodomains. It demonstrates 15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains. BAZ2-ICR has been shown to displace BAZ2 bromodomains in living cells by demonstrating accelerated FRAP recovery at 1 μM in the BAZ2A FRAP assay. See the Structural Genomics Consortium (SGC) website for more information.Suppliers and manufacturers
TargetMol Chemicals Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Shenzhen Shengda Pharma Limited
Zhejiang J&C Biological Technology Co.,Limited
Hangzhou MolCore BioPharmatech Co.,Ltd.
Zibo Hangyu Biotechnology Development Co., Ltd
Jilin Chinese Academy of Sciences-yanshen Technology
Aladdin Scientific
Shanghai Boyle Chemical Co., Ltd.
ShangHai Caerulum Pharma Discovery Co., Ltd.