2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide
![2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide price.](/CAS/GIF/304896-28-4.gif)
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- $30 - $927.76
- Product name: 2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide
- CAS: 304896-28-4
- MF: C23H13Cl2N3O2
- MW: 434.27
- EINECS:
- MDL Number:MFCD01909444
- Synonyms:2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide;AGK2;SIRT2 Inhibitor, AGK2;2-Cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(quinolin-5-yl)acrylamide;SIRT2 Inhibitor, AGK2 - CAS 304896-28-4 - Calbiochem;CS-2248;AGK2;AGK-2;AGK 2;2-Propenamide, 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-
30 prices
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Brand
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 1MG
- 5mg
- 10mg
- 25mg
- 50mg
- 10mM(in 1mL DMSO)
- 100mg
- 1g
- ManufacturerAmbeed
- Product numberA480363
- Product descriptionAGK2 98+%
- Packaging5mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA480363
- Product descriptionAGK2 98+%
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA480363
- Product descriptionAGK2 98+%
- Packaging25mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA480363
- Product descriptionAGK2 98+%
- Packaging1g
- Price$746
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000988
- Product descriptionAGK2 95.00%
- Packaging1MG
- Price$135.45
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000988
- Product descriptionAGK2 95.00%
- Packaging5MG
- Price$674.64
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000988
- Product descriptionAGK2 95.00%
- Packaging25MG
- Price$927.76
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7323
- Product descriptionAGK2
- Packaging10mM(in 1mL DMSO)
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7323
- Product descriptionAGK2
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7323
- Product descriptionAGK2
- Packaging50mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13145
- Product descriptionAGK2 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13145
- Product descriptionAGK2 ≥98%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13145
- Product descriptionAGK2 ≥98%
- Packaging10mg
- Price$169
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13145
- Product descriptionAGK2 ≥98%
- Packaging25mg
- Price$381
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-7830
- Product descriptionAGK2 99.62%
- Packaging5mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-7830
- Product descriptionAGK2 99.62%
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Ambeed | A480363 | AGK2 98+% | 5mg | $30 | 2021-12-16 | Buy |
| Ambeed | A480363 | AGK2 98+% | 10mg | $50 | 2021-12-16 | Buy |
| Ambeed | A480363 | AGK2 98+% | 25mg | $84 | 2021-12-16 | Buy |
| Ambeed | A480363 | AGK2 98+% | 1g | $746 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000988 | AGK2 95.00% | 1MG | $135.45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000988 | AGK2 95.00% | 5MG | $674.64 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000988 | AGK2 95.00% | 25MG | $927.76 | 2021-12-16 | Buy |
| ApexBio Technology | B7323 | AGK2 | 10mM(in 1mL DMSO) | $85 | 2021-12-16 | Buy |
| ApexBio Technology | B7323 | AGK2 | 10mg | $120 | 2021-12-16 | Buy |
| ApexBio Technology | B7323 | AGK2 | 50mg | $400 | 2021-12-16 | Buy |
| Cayman Chemical | 13145 | AGK2 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 13145 | AGK2 ≥98% | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 13145 | AGK2 ≥98% | 10mg | $169 | 2024-03-01 | Buy |
| Cayman Chemical | 13145 | AGK2 ≥98% | 25mg | $381 | 2024-03-01 | Buy |
| ChemScene | CS-7830 | AGK2 99.62% | 5mg | $85 | 2021-12-16 | Buy |
| ChemScene | CS-7830 | AGK2 99.62% | 10mg | $120 | 2021-12-16 | Buy |
Properties
Boiling point :675.1±55.0 °C(Predicted)
Density :1.445±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :Yellow solid
pka :8.87±0.43(Predicted)
color :White to Yellow to Orange
Density :1.445±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :Yellow solid
pka :8.87±0.43(Predicted)
color :White to Yellow to Orange
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Mammalian sirtuin 2 (SIRT2) is a nicotinamide adenine dinucleotide-dependent histone deacetylase (HDAC) with roles in cell cycle progression and tumorigenesis. AGK2 is a cell-permeable, selective inhibitor of SIRT2 (IC50 = 3.5 μM) that minimally affects either SIRT1 or SIRT3 at 10-fold higher levels. It rescues dopamine neurons from α-synuclein toxicity in both in vitro and in vivo Parkinson’s disease models, mimicking the effect of siRNA-mediated blockade of SIRT2 expression. AGK2 may be a useful tool for studying the roles of SIRT2 in neurodegeneration and aging, as well as cell cycle progression and tumorigenesis.More related product prices
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Suppliers and manufacturers
career henan chemical co
![2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide](https://img.chemicalbook.com/ProductImageEN/2020-2/small/41e91511-f58c-41bc-ab13-491db11871b1.jpg)
ATK CHEMICAL COMPANY LIMITED
Hubei Jusheng Technology Co.,Ltd.
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
Dideu Industries Group Limited
InvivoChem
Nantong HI-FUTURE Biology Co., Ltd.
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
$3.00 /1KG
2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide CAS:304896-28-4
2-Cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide CAS:304896-28-4