4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE
![4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE price.](/CAS/GIF/606-58-6.gif)
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- $25 - $450
- Product name: 4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE
- CAS: 606-58-6
- MF: C12H13N5O4
- MW: 291.26
- EINECS:
- MDL Number:MFCD00866513
- Synonyms:NSC 63701;NSC 99843;TOYOCAMYCIN;3-d)pyrimidine-5-carbonitrile,4-amino-7-beta-d-ribofuranosyl-7h-pyrrolo( ;4-amino-5-cyano-7-(d-ribofuranosyl)-7h-pyrrolo(2,3-d)pyrimidine ;4-amino-7-beta-d-ribofuranosyl-7h-pyrrolo(2,3-d)pyrimidine-5-carbonitrile ;a-399-y4 ;ahygroscopin-b
24 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10MG
- 50
- 25mg
- 50mg
- 100mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0015849
- Product description4-AMINO-7-BETA-D-RIBOFURANOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE 95.00%
- Packaging10MG
- Price$197.4
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7795
- Product descriptionToyocamycin
- Packaging50mg
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberNT44985
- Product descriptionToyocamycin
- Packaging5mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberNT44985
- Product descriptionToyocamycin
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberNT44985
- Product descriptionToyocamycin
- Packaging25mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberNT44985
- Product descriptionToyocamycin
- Packaging50mg
- Price$275
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberNT44985
- Product descriptionToyocamycin
- Packaging100mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17371
- Product descriptionToyocamycin ≥98%
- Packaging1mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17371
- Product descriptionToyocamycin ≥98%
- Packaging5mg
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17371
- Product descriptionToyocamycin ≥98%
- Packaging10mg
- Price$63
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17371
- Product descriptionToyocamycin ≥98%
- Packaging25mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0026179
- Product descriptionToyocamycin >99.0%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0026179
- Product descriptionToyocamycin >99.0%
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0026179
- Product descriptionToyocamycin >99.0%
- Packaging50mg
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0026179
- Product descriptionToyocamycin >99.0%
- Packaging100mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD70000821
- Product description4-Amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 97%
- Packaging10mg
- Price$170
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0015849 | 4-AMINO-7-BETA-D-RIBOFURANOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE 95.00% | 10MG | $197.4 | 2021-12-16 | Buy |
| ApexBio Technology | B7795 | Toyocamycin | 50mg | $410 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NT44985 | Toyocamycin | 5mg | $60 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NT44985 | Toyocamycin | 10mg | $95 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NT44985 | Toyocamycin | 25mg | $175 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NT44985 | Toyocamycin | 50mg | $275 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NT44985 | Toyocamycin | 100mg | $450 | 2021-12-16 | Buy |
| Cayman Chemical | 17371 | Toyocamycin ≥98% | 1mg | $25 | 2021-12-16 | Buy |
| Cayman Chemical | 17371 | Toyocamycin ≥98% | 5mg | $56 | 2021-12-16 | Buy |
| Cayman Chemical | 17371 | Toyocamycin ≥98% | 10mg | $63 | 2021-12-16 | Buy |
| Cayman Chemical | 17371 | Toyocamycin ≥98% | 25mg | $125 | 2021-12-16 | Buy |
| ChemScene | CS-0026179 | Toyocamycin >99.0% | 5mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-0026179 | Toyocamycin >99.0% | 10mg | $75 | 2021-12-16 | Buy |
| ChemScene | CS-0026179 | Toyocamycin >99.0% | 50mg | $260 | 2021-12-16 | Buy |
| ChemScene | CS-0026179 | Toyocamycin >99.0% | 100mg | $450 | 2021-12-16 | Buy |
| Crysdot | CD70000821 | 4-Amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 97% | 10mg | $170 | 2021-12-16 | Buy |
Properties
Melting point :243°; mp 239-243°
alpha :D16 -45.7° (c = 1.05 in 0.1N HCl)
Boiling point :433.28°C (rough estimate)
Density :1.3067 (rough estimate)
refractive index :1.7000 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble0.90 - 1.10mg/mL, clear, colorless
form :solid
pka :12.31±0.70(Predicted)
color :White or off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
alpha :D16 -45.7° (c = 1.05 in 0.1N HCl)
Boiling point :433.28°C (rough estimate)
Density :1.3067 (rough estimate)
refractive index :1.7000 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble0.90 - 1.10mg/mL, clear, colorless
form :solid
pka :12.31±0.70(Predicted)
color :White or off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Toyocamycin is a natural adenosine analog first isolated from Streptomyces and shown in early studies to be cytotoxic to bacteria, fungi, and cancer cells and to have antiviral activities. Toyocamycin prevents IRE1α-induced mRNA cleavage (IC50 = 80 nM) and inhibits constitutive activation of XBP1 in multiple myeloma cell lines. It is used to study IRE1α action in the endoplasmic reticulum stress response, particularly in the context of cancer. It also inhibits phosphatidylinositol kinase in vitro (IC50 = 3.3 μg/ml), but not in cells, and blocks the ribosomal RNA-processing kinase Rio1 (IC50 = ~30 nM).More related product prices
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