Phenol, 2-Methoxy-5-[[[(1E)-2-(2,4,6-triMethoxyphenyl)ethenyl]sulfonyl]Methyl]-, 1-(dihydrogen phosphate)
![Phenol, 2-Methoxy-5-[[[(1E)-2-(2,4,6-triMethoxyphenyl)ethenyl]sulfonyl]Methyl]-, 1-(dihydrogen phosphate) price.](/CAS/20150408/GIF/865783-99-9.gif)
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- $37 - $1800
- Product name: Phenol, 2-Methoxy-5-[[[(1E)-2-(2,4,6-triMethoxyphenyl)ethenyl]sulfonyl]Methyl]-, 1-(dihydrogen phosphate)
- CAS: 865783-99-9
- MF: C19H23O10PS
- MW: 474.42
- EINECS:
- MDL Number:MFCD22665751
- Synonyms:Phenol, 2-Methoxy-5-[[[(1E)-2-(2,4,6-triMethoxyphenyl)ethenyl]sulfonyl]Methyl]-, 1-(dihydrogen phosphate);Briciclib,ON-014185;ON-014185;(E)-5-[[(2,4,6-Trimethoxystyryl)sulfonyl]methyl]-2-methoxyphenyl dihydrogen phosphate;2-Methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methy l)phenyl dihydrogen phosphate;Briciclib(ON 013105,ON 014185);Briciclib, >98%;ON013105;ON014185;ON-013105;ON-014185
27 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number6120CS
- Product descriptionBriciclib
- Packaging5mg
- Price$276
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6120CS
- Product descriptionBriciclib
- Packaging10mg
- Price$413
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6120CS
- Product descriptionBriciclib
- Packaging25mg
- Price$735
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA265253
- Product descriptionBriciclib 98+%
- Packaging1mg
- Price$38
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA265253
- Product descriptionBriciclib 98+%
- Packaging5mg
- Price$76
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA265253
- Product descriptionBriciclib 98+%
- Packaging10mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA265253
- Product descriptionBriciclib 98+%
- Packaging25mg
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA265253
- Product descriptionBriciclib 98+%
- Packaging50mg
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA265253
- Product descriptionBriciclib 98+%
- Packaging100mg
- Price$219
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA265253
- Product descriptionBriciclib 98+%
- Packaging250mg
- Price$368
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA265253
- Product descriptionBriciclib 98+%
- Packaging1g
- Price$925
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22989
- Product descriptionBriciclib ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22989
- Product descriptionBriciclib ≥98%
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22989
- Product descriptionBriciclib ≥98%
- Packaging10mg
- Price$283
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22989
- Product descriptionBriciclib ≥98%
- Packaging25mg
- Price$573
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5589
- Product descriptionBriciclib 99.65%
- Packaging1mg
- Price$90
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 6120CS | Briciclib | 5mg | $276 | 2021-12-16 | Buy |
| AK Scientific | 6120CS | Briciclib | 10mg | $413 | 2021-12-16 | Buy |
| AK Scientific | 6120CS | Briciclib | 25mg | $735 | 2021-12-16 | Buy |
| Ambeed | A265253 | Briciclib 98+% | 1mg | $38 | 2021-12-16 | Buy |
| Ambeed | A265253 | Briciclib 98+% | 5mg | $76 | 2021-12-16 | Buy |
| Ambeed | A265253 | Briciclib 98+% | 10mg | $99 | 2021-12-16 | Buy |
| Ambeed | A265253 | Briciclib 98+% | 25mg | $129 | 2021-12-16 | Buy |
| Ambeed | A265253 | Briciclib 98+% | 50mg | $168 | 2021-12-16 | Buy |
| Ambeed | A265253 | Briciclib 98+% | 100mg | $219 | 2021-12-16 | Buy |
| Ambeed | A265253 | Briciclib 98+% | 250mg | $368 | 2021-12-16 | Buy |
| Ambeed | A265253 | Briciclib 98+% | 1g | $925 | 2021-12-16 | Buy |
| Cayman Chemical | 22989 | Briciclib ≥98% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 22989 | Briciclib ≥98% | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 22989 | Briciclib ≥98% | 10mg | $283 | 2024-03-01 | Buy |
| Cayman Chemical | 22989 | Briciclib ≥98% | 25mg | $573 | 2024-03-01 | Buy |
| ChemScene | CS-5589 | Briciclib 99.65% | 1mg | $90 | 2021-12-16 | Buy |
Properties
storage temp. :Sealed in dry,Room Temperature
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml
form :A crystalline solid
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml
form :A crystalline solid
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Briciclib is a water soluble derivative of ON 013100, a small molecule that binds to and inhibits eukaryotic translation initiation factor 4E (eIF4E). Briciclib inhibits proliferation of JEKO-1 and Mino mantle cell leukemia (MCL), MCF-7 and MDA-MB-231 breast, AGS gastric, and OE19, OE33, and LFO-1 esophageal cancer cell lines with GI50 values ranging from 9.8 to 12.2 nM. It reduces expression of cyclin D1 and c-Myc, markers of eIF4E activity, in breast and MCL cancer cell lines in a dose-dependent manner. Briciclib also induces expression of the pro-apoptotic proteins p53 and cleaved caspase-3.Suppliers and manufacturers
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