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ChemicalBook >> CAS DataBase List >> 4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,4-dihydro-5-[(5-nitro-2-thiazolyl)thio]-3H-1,2,4-triazol-3-one

4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,4-dihydro-5-[(5-nitro-2-thiazolyl)thio]-3H-1,2,4-triazol-3-one

4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,4-dihydro-5-[(5-nitro-2-thiazolyl)thio]-3H-1,2,4-triazol-3-one price.
  • $32 - $2839
  • Product name: 4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,4-dihydro-5-[(5-nitro-2-thiazolyl)thio]-3H-1,2,4-triazol-3-one
  • CAS: 883065-90-5
  • MF: C13H9N5O5S2
  • MW: 379.37
  • EINECS:
  • MDL Number:MFCD01313575
  • Synonyms:4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,4-dihydro-5-[(5-nitro-2-thiazolyl)thio]-3H-1,2,4-triazol-3-one;BI 78D3;4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-((5-nitro-thiazol-2-yl)thio)-1H-1,2,4-triazol-5(4H)-one;4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-((5-nitro-thiazol-2-yl)thio)-1H-1,2,4-triazol-5(4H)-;JNK Inhibitor X, BI-78D3 ;4-(2,3-Dihydrobenzol[b][1,4]dioxin-6-yl)-5-(5-nitrothiazol-2-ylthio)-4H-1,2,4-triazol-3-ol;JNK Inhibitor X, BI-78D3 - CAS 883065-90-5 - Calbiochem;3H-1,2,4-Triazol-3-one, 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,4-dihydro-5-[(5-nitro-2-thiazolyl)thio]-
Price43 Properties Safety Information Description
43 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 2.5mg
  • 50
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1000mg
  • 1g
  • ManufacturerAK Scientific
  • Product number4092AC
  • Product description4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-((5-nitrothiazol-2-yl)thio)-1H-1,2,4-triazol-5(4H)-one
  • Packaging1mg
  • Price$82
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4092AC
  • Product description4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-((5-nitrothiazol-2-yl)thio)-1H-1,2,4-triazol-5(4H)-one
  • Packaging2mg
  • Price$113
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA166355
  • Product descriptionBI-78D3 98+%
  • Packaging5mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA166355
  • Product descriptionBI-78D3 98+%
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA166355
  • Product descriptionBI-78D3 98+%
  • Packaging25mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA166355
  • Product descriptionBI-78D3 98+%
  • Packaging50mg
  • Price$247
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA166355
  • Product descriptionBI-78D3 98+%
  • Packaging100mg
  • Price$321
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0002508
  • Product description4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-2,4-DIHYDRO-5-[(5-NITRO-2-THIAZOLYL)THIO]-3H-1,2,4-TRIAZOL-3-ONE 95.00%
  • Packaging5MG
  • Price$498.42
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0004998
  • Product descriptionBI-78D3 95.00%
  • Packaging10MG
  • Price$709.46
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0004998
  • Product descriptionBI-78D3 95.00%
  • Packaging50MG
  • Price$1267.33
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB9011
  • Product descriptionBI78D3
  • Packaging5mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB9011
  • Product descriptionBI78D3
  • Packaging10mg
  • Price$213
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB9011
  • Product descriptionBI78D3
  • Packaging25mg
  • Price$449
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB9011
  • Product descriptionBI78D3
  • Packaging100mg
  • Price$1276
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0178
  • Product descriptionBI-78D3
  • Packaging1mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0178
  • Product descriptionBI-78D3
  • Packaging5mg
  • Price$109
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4092AC 4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-((5-nitrothiazol-2-yl)thio)-1H-1,2,4-triazol-5(4H)-one 1mg $82 2021-12-16 Buy
AK Scientific 4092AC 4-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-((5-nitrothiazol-2-yl)thio)-1H-1,2,4-triazol-5(4H)-one 2mg $113 2021-12-16 Buy
Ambeed A166355 BI-78D3 98+% 5mg $73 2021-12-16 Buy
Ambeed A166355 BI-78D3 98+% 10mg $110 2021-12-16 Buy
Ambeed A166355 BI-78D3 98+% 25mg $190 2021-12-16 Buy
Ambeed A166355 BI-78D3 98+% 50mg $247 2021-12-16 Buy
Ambeed A166355 BI-78D3 98+% 100mg $321 2021-12-16 Buy
American Custom Chemicals Corporation KIN0002508 4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-2,4-DIHYDRO-5-[(5-NITRO-2-THIAZOLYL)THIO]-3H-1,2,4-TRIAZOL-3-ONE 95.00% 5MG $498.42 2021-12-16 Buy
American Custom Chemicals Corporation RDL0004998 BI-78D3 95.00% 10MG $709.46 2021-12-16 Buy
American Custom Chemicals Corporation RDL0004998 BI-78D3 95.00% 50MG $1267.33 2021-12-16 Buy
ApexBio Technology B9011 BI78D3 5mg $139 2021-12-16 Buy
ApexBio Technology B9011 BI78D3 10mg $213 2021-12-16 Buy
ApexBio Technology B9011 BI78D3 25mg $449 2021-12-16 Buy
ApexBio Technology B9011 BI78D3 100mg $1276 2021-12-16 Buy
Apolloscientific BISN0178 BI-78D3 1mg $66 2021-12-16 Buy
Apolloscientific BISN0178 BI-78D3 5mg $109 2021-12-16 Buy
Next Last

Properties

Density :1.92±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: >10mg/mL
form :powder
pka :2.76±0.20(Predicted)
color :tan

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

BI 78D3 is a competitive JNK (c-Jun N-terminal kinases) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. BI 78D3 inhibits JIP1(JNK interacting protein 1)-JNK binding (IC50 = 500 nM).

Suppliers and manufacturers

career henan chemical co
4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-1H-1,2,4-triazol-5-one
$1.00 /1KG
4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-1H-1,2,4-triazol-5-one CAS:883065-90-5
ATK CHEMICAL COMPANY LIMITED
Alchem Pharmtech,Inc.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
LEAP CHEM CO., LTD.
Nantong HI-FUTURE Biology Co., Ltd.
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Shanghai Acmec Biochemical Technology Co., Ltd.