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ChemicalBook >> CAS DataBase List >> 1-PALMITOYL-2-(4-CARBOXYBUTANOYL)-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE

1-PALMITOYL-2-(4-CARBOXYBUTANOYL)-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE

1-PALMITOYL-2-(4-CARBOXYBUTANOYL)-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE price.
  • $26 - $504.05
  • Product name: 1-PALMITOYL-2-(4-CARBOXYBUTANOYL)-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE
  • CAS: 89947-79-5
  • MF: C29H56NO10P
  • MW: 609.74
  • EINECS:
  • MDL Number:MFCD05863933
  • Synonyms:PGPC;1-PALMITOYL-2-(4-CARBOXYBUTANOYL)-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE;1-palMitoyl-2-glutaryl-sn-glycero-3-phosphocholine;1-PALMITOYL-2-GLUTARYL-SN-GLYCERO-3-PHOSPHOCHOLINE;PGPC;1-palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine, powder;(2S,5S)-5-Amino-7-carboxy-1-hydroxy-4-oxo-3-(palmitoyloxy)heptan-2-yl (2-(trimethylammonio)ethyl) phosphate;3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(4-carboxy-1-oxobutoxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-, innersalt, 4-oxide, (7R)-
6 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5MG
  • 10mg
  • ManufacturerAK Scientific
  • Product number1985AH
  • Product descriptionPGPC
  • Packaging1mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000409
  • Product description1-PALMITOYL-2-GLUTARYL PHOSPHATIDYLCHOLINE 95.00%
  • Packaging5MG
  • Price$504.05
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10044
  • Product descriptionPGPC ≥98%
  • Packaging500μg
  • Price$26
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10044
  • Product descriptionPGPC ≥98%
  • Packaging1mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10044
  • Product descriptionPGPC ≥98%
  • Packaging5mg
  • Price$192
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10044
  • Product descriptionPGPC ≥98%
  • Packaging10mg
  • Price$332
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1985AH PGPC 1mg $145 2021-12-16 Buy
American Custom Chemicals Corporation LIP0000409 1-PALMITOYL-2-GLUTARYL PHOSPHATIDYLCHOLINE 95.00% 5MG $504.05 2021-12-16 Buy
Cayman Chemical 10044 PGPC ≥98% 500μg $26 2024-03-01 Buy
Cayman Chemical 10044 PGPC ≥98% 1mg $49 2024-03-01 Buy
Cayman Chemical 10044 PGPC ≥98% 5mg $192 2024-03-01 Buy
Cayman Chemical 10044 PGPC ≥98% 10mg $332 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO: 1 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 5 mg/ml

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes and activate polymorphonuclear leukocytes. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. One of these substances isolated from oxLDL and identified as azelaoyl PAF is a potent PPARγ agonist. 1-Palmitoyl-2-glutaryl phosphatidylcholine (PGPC) and 1-(palmitoyl)-2-(5-oxovaleroyl) phosphatidylcholine (POV-PC) are closely related compounds with strikingly different activity. PGPC treatment of vascular endothelial cells induces the expression of both E-selectin and VCAM-1, and increases endothelial cell binding by both neutrophils and monocytes. This contrasts with POV-PC treatment, which stimulates only monocyte binding, and strongly inhibits the LPS-induced binding of neutrophils.