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ChemicalBook >> CAS DataBase List >> CP 471,474

CP 471,474

CP 471,474 price.
  • $32 - $4046
  • Product name: CP 471,474
  • CAS: 210755-45-6
  • MF: C16H17FN2O5S
  • MW: 368.38
  • EINECS:
  • MDL Number:MFCD16618408
  • Synonyms:PF-1626077;CP 471,474;2-[[[4-(4-Fluorophenoxy)phenyl]sulfonyl]amino]-N-hydroxy-2-methylpropanamide;2-(4-(4-Fluorophenoxy)phenylsulfonamido)-N-hydroxy-2-methylpropanamide;Propanamide, 2-[[[4-(4-fluorophenoxy)phenyl]sulfonyl]amino]-N-hydroxy-2-methyl-
14 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 2x10mg
  • 50
  • 25mg
  • 50mg
  • 100MG
  • 10
  • 1g
  • ManufacturerAK Scientific
  • Product number3752BB
  • Product description2-[[[4-(4-Fluorophenoxy)phenyl]sulfonyl]amino]-N-hydroxy-2-methylpropanamide
  • Packaging1g
  • Price$4046
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010256
  • Product description2-[[[4-(4-FLUOROPHENOXY)PHENYL]SULFONYL]AMINO]-N-HYDROXY-2-METHYLPROPANAMIDE 95.00%
  • Packaging100MG
  • Price$1593.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4435
  • Product descriptionCP471474
  • Packaging10mg
  • Price$251
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4435
  • Product descriptionCP471474
  • Packaging50mg
  • Price$1053
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2104
  • Product descriptionCP471474 99%
  • Packaging2x10mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29442
  • Product descriptionCP 471,474
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29442
  • Product descriptionCP 471,474
  • Packaging5mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29442
  • Product descriptionCP 471,474
  • Packaging10mg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerMatrix Scientific
  • Product number147769
  • Product description2-[[[4-(4-Fluorophenoxy)phenyl]sulfonyl]amino]-N-hydroxy-2-methylpropanamide 95%
  • Packaging1g
  • Price$2960
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPZ0137
  • Product descriptionCP-471474 ≥98% (HPLC)
  • Packaging5mg
  • Price$130
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPZ0137
  • Product descriptionCP-471474 ≥98% (HPLC)
  • Packaging25mg
  • Price$404
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number3780
  • Product descriptionCP471474 ≥97%(HPLC)
  • Packaging10
  • Price$159
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number3780
  • Product descriptionCP471474 ≥97%(HPLC)
  • Packaging50
  • Price$603
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC781305
  • Product descriptionCP-471474
  • Packaging25mg
  • Price$270
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3752BB 2-[[[4-(4-Fluorophenoxy)phenyl]sulfonyl]amino]-N-hydroxy-2-methylpropanamide 1g $4046 2021-12-16 Buy
American Custom Chemicals Corporation API0010256 2-[[[4-(4-FLUOROPHENOXY)PHENYL]SULFONYL]AMINO]-N-HYDROXY-2-METHYLPROPANAMIDE 95.00% 100MG $1593.9 2021-12-16 Buy
ApexBio Technology A4435 CP471474 10mg $251 2021-12-16 Buy
ApexBio Technology A4435 CP471474 50mg $1053 2021-12-16 Buy
Axon Medchem Axon2104 CP471474 99% 2x10mg $154 2021-12-16 Buy
Cayman Chemical 29442 CP 471,474 1mg $32 2024-03-01 Buy
Cayman Chemical 29442 CP 471,474 5mg $86 2024-03-01 Buy
Cayman Chemical 29442 CP 471,474 10mg $153 2024-03-01 Buy
Matrix Scientific 147769 2-[[[4-(4-Fluorophenoxy)phenyl]sulfonyl]amino]-N-hydroxy-2-methylpropanamide 95% 1g $2960 2021-12-16 Buy
Sigma-Aldrich PZ0137 CP-471474 ≥98% (HPLC) 5mg $130 2024-03-01 Buy
Sigma-Aldrich PZ0137 CP-471474 ≥98% (HPLC) 25mg $404 2024-03-01 Buy
Tocris 3780 CP471474 ≥97%(HPLC) 10 $159 2021-12-16 Buy
Tocris 3780 CP471474 ≥97%(HPLC) 50 $603 2021-12-16 Buy
TRC C781305 CP-471474 25mg $270 2021-12-16 Buy

Properties

Melting point :135-137°C (dec.)
Density :1.375±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥20mg/mL
pka :9.33±0.50(Predicted)
form :powder
color :white to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CP 471,474 is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with IC50 values of 0.7, 16, 13, and 0.9 nM for MMP-2, MMP-3, MMP-9, and MMP-13, respectively. It is selective for these MMPs over MMP-1 (IC50 = 1,170 nM). CP 471,474 reduces left ventricular enlargement and decreases the incidence of cardiac rupture in mouse models of myocardial infarction when administered at doses of 120 mg/kg twice per day and 240 mg/kg per day, respectively.

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