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ChemicalBook >> CAS DataBase List >> Lafutidine

Lafutidine

Lafutidine price.
  • $6 - $2425.5
  • Product name: Lafutidine
  • CAS: 118288-08-7
  • MF: C22H29N3O4S
  • MW: 431.55
  • EINECS:601-513-8
  • MDL Number:MFCD00867520
  • Synonyms:n-(4-(4-piperidinylmethyl)pyridyl-2-oxy)butenyl-2-(furfurylsulfinyl)acetamide;2-((Furan-2-ylMethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylMethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetaMide;(Z)-2-((Furan-2-ylMethyl)sulfinyl)-N-(4-((3-(piperidin-1-ylMethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetaMide;Adefovir Dipivioxil;(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((3-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl);(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((3-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-;LAFUTIDINE(SUBJECTTOPATENTFREE);118288-08-07
41 prices
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Brand
  • AccelPharmtech
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TCI Chemical
  • TRC
Package
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 0.25g
  • 1g
  • 10mM(in 1mL DMSO)
  • 5g
  • 25G
  • 100G
  • ManufacturerAccelPharmtech
  • Product numberAT6292
  • Product descriptionLafutidine 99.00%
  • Packaging100G
  • Price$960
  • Updated2021-12-16
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberAT6292
  • Product descriptionLafutidine 99.00%
  • Packaging25G
  • Price$460
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1731
  • Product descriptionLafutidine 98%
  • Packaging0.25g
  • Price$620
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH692
  • Product descriptionLafutidine
  • Packaging250mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101474
  • Product description(+)-(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide 99+%
  • Packaging250mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101474
  • Product description(+)-(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide 99+%
  • Packaging1g
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101474
  • Product description(+)-(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide 99+%
  • Packaging5g
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003112
  • Product descriptionLAFUTIDINE 95.00%
  • Packaging1G
  • Price$2425.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1575
  • Product descriptionLafutidine
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1575
  • Product descriptionLafutidine
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1575
  • Product descriptionLafutidine
  • Packaging50mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS425751
  • Product descriptionLafutidine ≥99%
  • Packaging100mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS425751
  • Product descriptionLafutidine ≥99%
  • Packaging250mg
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS425751
  • Product descriptionLafutidine ≥99%
  • Packaging1g
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2805
  • Product descriptionLafutidine
  • Packaging10mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2805
  • Product descriptionLafutidine
  • Packaging100mg
  • Price$145
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AccelPharmtech AT6292 Lafutidine 99.00% 100G $960 2021-12-16 Buy
AccelPharmtech AT6292 Lafutidine 99.00% 25G $460 2021-12-16 Buy
AHH API-1731 Lafutidine 98% 0.25g $620 2021-12-16 Buy
AK Scientific H692 Lafutidine 250mg $72 2021-12-16 Buy
Ambeed A101474 (+)-(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide 99+% 250mg $15 2021-12-16 Buy
Ambeed A101474 (+)-(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide 99+% 1g $37 2021-12-16 Buy
Ambeed A101474 (+)-(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((4-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide 99+% 5g $129 2021-12-16 Buy
American Custom Chemicals Corporation API0003112 LAFUTIDINE 95.00% 1G $2425.5 2021-12-16 Buy
ApexBio Technology B1575 Lafutidine 10mg $50 2021-12-16 Buy
ApexBio Technology B1575 Lafutidine 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B1575 Lafutidine 50mg $120 2021-12-16 Buy
Arctom AS425751 Lafutidine ≥99% 100mg $6 2021-12-16 Buy
Arctom AS425751 Lafutidine ≥99% 250mg $9 2021-12-16 Buy
Arctom AS425751 Lafutidine ≥99% 1g $19 2021-12-16 Buy
AvaChem 2805 Lafutidine 10mg $45 2021-12-16 Buy
AvaChem 2805 Lafutidine 100mg $145 2021-12-16 Buy

Properties

Melting point :92.7-94.9°
Boiling point :704.2±60.0 °C(Predicted)
Density :1.252±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
Water Solubility :Insoluble in water
solubility :DMF:5.0(Max Conc. mg/mL);11.59(Max Conc. mM)
DMSO:48.67(Max Conc. mg/mL);112.77(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:10):0.09(Max Conc. mg/mL);0.21(Max Conc. mM)
Ethanol:9.0(Max Conc. mg/mL);20.86(Max Conc. mM) form :powder to crystal
pka :13.13±0.46(Predicted)
color :White to Orange to Green
CAS DataBase Reference :118288-08-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Lafutidine was launched in Japan for the treatment of gastritis, reflux oesophagitis and peptic ulcers. It can be prepared in eight steps from 4-(2-tetrahydropyranyloxy)-2(Z)-butenl- ol. Lafutidine is a potent and longer-acting H2 antagonist compared to other marketed compounds of its class such as cimetidine and famotidine. In contrast to other commercially available H2 antagonists, lafutidine also exerts a gastroprotective action probably via capsaicin-sensitive afferent nerves. It was clinically effective in the treatment of nonsteroidal antiinflammatory drug-induced ulcer in patients refractory to existing antiulcer agents.

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