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ChemicalBook >> CAS DataBase List >> OLOMOUCINE

OLOMOUCINE

OLOMOUCINE price.
  • $50.5 - $198
  • Product name: OLOMOUCINE
  • CAS: 101622-51-9
  • MF: C15H18N6O
  • MW: 298.34
  • EINECS:
  • MDL Number:MFCD00189360
  • Synonyms:6-BENYLAMINO-2-(2-HYDROXYETHYLAMINO)-9-METHYLPURINE;6-BENZYLAMINO-2-(2-HYDROXYETHYLAMINO)-9-METHYLPURINE;2-[[9-METHYL-6[(PHENYLMETHYL)AMINO]-9H-PURIN-2-YL]AMINO]-ETHANOL;2-(2-HYDROXYETHYLAMINO)-6-BENZYLAMINO-9-METHYLPURINE;N2-[(2-HYDROXYETHYL)]-N6-BENZYLADENINE;OLOMOUCINE;OLOMOUCINE SYNTHETIC >95%;Olomoucine,highpurity
4 prices
Selected condition:

Brand

  • Sigma-Aldrich

Package

  • 1mg
  • 5mg
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 495620 Olomoucine 1mg $50.5 2017-11-08 Buy
Sigma-Aldrich O0886 Olomoucine ≥98% (HPLC) 1mg $64.1 2017-11-08 Buy
Sigma-Aldrich 495620 Olomoucine 5mg $195 2017-11-08 Buy
Sigma-Aldrich O0886 Olomoucine ≥98% (HPLC) 5mg $198 2017-11-08 Buy

Properties

Melting point: :120-130 °C
Density  :1.36
storage temp.  :−20°C
form  :Solid
color  :White to off-white
CAS DataBase Reference :101622-51-9(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Olomoucine is a purine that acts as a competitive inhibitor of a variety of cell cycle regulating proteins with high specificity, which leads to the blockage of some cell cycle steps. The compound inhibits: Cdc2/cyclin B, Cdk2/cyclin A and Cdk2/cyclin E kinases, the brain Cdk5/p35 kinase and the ERK1/MAP-kinase. Olomoucine does not significantly inhibit Cdk4/cyclin D1 and Cdk6/cyclin D3 kinases. The compound can induce cell arrest at G1/S and the G2/M, due to its effect on Ckd2 and Cdcd2. Olomoucine also behaves as a competitive inhibitor for ATP and as a non-competitive inhibitor for histone H1 in terms of being Cdk substrates.

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