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ChemicalBook >> CAS DataBase List >> PF 3845

PF 3845

PF 3845 price.
  • $29 - $2240.7
  • Product name: PF 3845
  • CAS: 1196109-52-0
  • MF: C24H23F3N4O2
  • MW: 456.46
  • EINECS:
  • MDL Number:MFCD21365072
  • Synonyms:PF3845/PF-3845;N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide;PF 3845;4-(3-(5-(trifluoromethyl)pyridin-2-yloxy)benzyl)-N-(pyridin-3-yl)piperidine-1-carboxamide;N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide PF 3845;N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide hydrate;PF 3845 hydrate;N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxami
30 prices
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  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
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  • 1mg
  • 50
  • 25mg
  • 50mg
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  • 1g
  • ManufacturerAmbeed
  • Product numberA475760
  • Product descriptionN-(Pyridin-3-yl)-4-(3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzyl)piperidine-1-carboxamide 99+%
  • Packaging25mg
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA475760
  • Product descriptionN-(Pyridin-3-yl)-4-(3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzyl)piperidine-1-carboxamide 99+%
  • Packaging50mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA475760
  • Product descriptionN-(Pyridin-3-yl)-4-(3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzyl)piperidine-1-carboxamide 99+%
  • Packaging100mg
  • Price$221
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA475760
  • Product descriptionN-(Pyridin-3-yl)-4-(3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzyl)piperidine-1-carboxamide 99+%
  • Packaging250mg
  • Price$367
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007700
  • Product descriptionPF-3845 95.00%
  • Packaging10MG
  • Price$275.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007700
  • Product descriptionPF-3845 95.00%
  • Packaging100MG
  • Price$2240.7
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4374
  • Product descriptionPF-3845
  • Packaging10mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1711
  • Product descriptionPF3845 99%
  • Packaging50mg
  • Price$478.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181420
  • Product descriptionPF 3845 >98%
  • Packaging100mg
  • Price$1060.8
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFP102746
  • Product descriptionPF 3845
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFP102746
  • Product descriptionPF 3845
  • Packaging50mg
  • Price$332.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13279
  • Product descriptionPF-3845 ≥98%
  • Packaging1mg
  • Price$29
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13279
  • Product descriptionPF-3845 ≥98%
  • Packaging5mg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13279
  • Product descriptionPF-3845 ≥98%
  • Packaging10mg
  • Price$216
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13279
  • Product descriptionPF-3845 ≥98%
  • Packaging25mg
  • Price$469
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0419
  • Product descriptionPF-3845 99.90%
  • Packaging5mg
  • Price$66
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A475760 N-(Pyridin-3-yl)-4-(3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzyl)piperidine-1-carboxamide 99+% 25mg $104 2021-12-16 Buy
Ambeed A475760 N-(Pyridin-3-yl)-4-(3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzyl)piperidine-1-carboxamide 99+% 50mg $147 2021-12-16 Buy
Ambeed A475760 N-(Pyridin-3-yl)-4-(3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzyl)piperidine-1-carboxamide 99+% 100mg $221 2021-12-16 Buy
Ambeed A475760 N-(Pyridin-3-yl)-4-(3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzyl)piperidine-1-carboxamide 99+% 250mg $367 2021-12-16 Buy
American Custom Chemicals Corporation API0007700 PF-3845 95.00% 10MG $275.1 2021-12-16 Buy
American Custom Chemicals Corporation API0007700 PF-3845 95.00% 100MG $2240.7 2021-12-16 Buy
ApexBio Technology A4374 PF-3845 10mg $147 2021-12-16 Buy
Axon Medchem Axon1711 PF3845 99% 50mg $478.5 2021-12-16 Buy
Biorbyt Ltd orb181420 PF 3845 >98% 100mg $1060.8 2021-12-16 Buy
Biosynth Carbosynth FP102746 PF 3845 10mg $95 2021-12-16 Buy
Biosynth Carbosynth FP102746 PF 3845 50mg $332.5 2021-12-16 Buy
Cayman Chemical 13279 PF-3845 ≥98% 1mg $29 2024-03-01 Buy
Cayman Chemical 13279 PF-3845 ≥98% 5mg $121 2024-03-01 Buy
Cayman Chemical 13279 PF-3845 ≥98% 10mg $216 2024-03-01 Buy
Cayman Chemical 13279 PF-3845 ≥98% 25mg $469 2024-03-01 Buy
ChemScene CS-0419 PF-3845 99.90% 5mg $66 2021-12-16 Buy

Properties

Boiling point :623.6±55.0 °C(Predicted)
Density :1.323±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥45mg/mL
pka :14.14±0.40(Predicted)
form :powder
color :white to tan

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Fatty acid amide hydrolase (FAAH) degrades N-acyl ethanolamines (NAEs), including the endocannabinoid arachidonoyl ethanolamide (AEA). PF-3845 is a potent, selective, and irreversible inhibitor of FAAH (Ki = 0.23 μM). It covalently binds FAAH on Ser241 at the catalytic site, resulting in prolonged elevation of AEA in the brain and plasma in rats after treatment. PF-3845 significantly and persistently reduces inflammatory pain in rats through a cannabinoid receptor-dependent mechanism.

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