PLX3397 (Pexidartinib)
|
- $50 - $6850
- Product name: PLX3397 (Pexidartinib)
- CAS: 1029044-16-3
- MF: C20H15ClF3N5
- MW: 417.81
- EINECS:-0
- MDL Number:MFCD28900745
- Synonyms:5-((5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl);3-Pyridinemethanamine,N-[5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-;N-[5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine;PLX3397 (Pexidartinib);PLX339;5-((5-chloro-1H-pyrrolo[2,3-b]pyridin-2-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)pyridin-2-amine;5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine;CS-1695
29 prices
Selected condition：
Brand
- AK Scientific
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- 5g
- 10g
- 20g
- ManufacturerAK Scientific
- Product number2971DC
- Product descriptionPexidartinib
- Packaging25mg
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP76492
- Product descriptionPexidartinib
- Packaging25mg
- Price$87.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP76492
- Product descriptionPexidartinib
- Packaging100mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18271
- Product descriptionPexidartinib ≥98%
- Packaging5mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18271
- Product descriptionPexidartinib ≥98%
- Packaging10mg
- Price$115
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18271
- Product descriptionPexidartinib ≥98%
- Packaging25mg
- Price$270
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18271
- Product descriptionPexidartinib ≥98%
- Packaging50mg
- Price$419
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM149380
- Product description5-((5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)pyridin-2-amine 95%+
- Packaging100mg
- Price$325
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4256
- Product descriptionPexidartinib 99.64%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4256
- Product descriptionPexidartinib 99.64%
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4256
- Product descriptionPexidartinib 99.64%
- Packaging50mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4256
- Product descriptionPexidartinib 99.64%
- Packaging100mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4256
- Product descriptionPexidartinib 99.64%
- Packaging200mg
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4256
- Product descriptionPexidartinib 99.64%
- Packaging500mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4256
- Product descriptionPexidartinib 99.64%
- Packaging1g
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4256
- Product descriptionPexidartinib 99.64%
- Packaging2g
- Price$1250
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2971DC | Pexidartinib | 25mg | $168 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP76492 | Pexidartinib | 25mg | $87.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP76492 | Pexidartinib | 100mg | $190 | 2021-12-16 | Buy |
| Cayman Chemical | 18271 | Pexidartinib ≥98% | 5mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 18271 | Pexidartinib ≥98% | 10mg | $115 | 2024-03-01 | Buy |
| Cayman Chemical | 18271 | Pexidartinib ≥98% | 25mg | $270 | 2024-03-01 | Buy |
| Cayman Chemical | 18271 | Pexidartinib ≥98% | 50mg | $419 | 2024-03-01 | Buy |
| Chemenu | CM149380 | 5-((5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)pyridin-2-amine 95%+ | 100mg | $325 | 2021-12-16 | Buy |
| ChemScene | CS-4256 | Pexidartinib 99.64% | 5mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-4256 | Pexidartinib 99.64% | 10mg | $70 | 2021-12-16 | Buy |
| ChemScene | CS-4256 | Pexidartinib 99.64% | 50mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-4256 | Pexidartinib 99.64% | 100mg | $190 | 2021-12-16 | Buy |
| ChemScene | CS-4256 | Pexidartinib 99.64% | 200mg | $260 | 2021-12-16 | Buy |
| ChemScene | CS-4256 | Pexidartinib 99.64% | 500mg | $450 | 2021-12-16 | Buy |
| ChemScene | CS-4256 | Pexidartinib 99.64% | 1g | $750 | 2021-12-16 | Buy |
| ChemScene | CS-4256 | Pexidartinib 99.64% | 2g | $1250 | 2021-12-16 | Buy |
Properties
Density :1.458±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 10 mg/ml)
pka :12.81±0.40(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
CAS DataBase Reference :1029044-16-3
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 10 mg/ml)
pka :12.81±0.40(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
CAS DataBase Reference :1029044-16-3
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Colony stimulating factor-1 (CSF1) is a cytokine that is involved in the recruitment and activation of tissue macrophages. It exerts these effects by binding to its corresponding receptor tyrosine kinase, the cFMS/CSF1 receptor (CSF1R). Pexidartinib is a brain-penetrant inhibitor of CSF1R, as well as c-Kit and FLT3 (IC50s = 20, 10, and 160 nM in vitro, respectively). It has been used in combination with paclitaxel to block macrophage recruitment in mammary tumor-bearing mice, thus slowing primary tumor development and metastasis. Pexidartinib has also been used to block microglial stimulation of glioblastoma invasion in both cell culture and a mouse model of glioblastoma multiforme.More related product prices
2-AMINO-1-BUTANOL Boron 405169-16-6 ARRY-334543 Momelotinib CO-1686 CAL-101 Lestaurtinib Masitinib (AB1010) Decernotinib GPLG0634 X-376 INCB39110 905854-02-6 SU 6668 PLX5622 918505-84-7 PLX8394Related product price
- 2-AMINO-1-BUTANOL
$8-1040 - Boron
$45-4696.38 - 405169-16-6
$92-6121.5
