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ChemicalBook >> CAS DataBase List >> Probenecid

Probenecid

Probenecid price.
  • $15 - $1800
  • Product name: Probenecid
  • CAS: 57-66-9
  • MF: C13H19NO4S
  • MW: 285.36
  • EINECS:200-344-3
  • MDL Number:MFCD00038402
  • Synonyms:4-[(dipropylamino)sulfonyl]-benzoicaci ;Probenecid,98%;NSC 18786;Probenecid (200 mg);4-(DI-N-PROPYLAMINO)SULFONYL BENZOIC ACID 4-[(DIPROPYLAMINO)SULFONYL]BENZOIC ACID AKOS BBS-00002773 LABOTEST-BB LT00772250 P-[DIPROPYLSULFAMOYL]BENZOIC ACID PROBENECID 4-((dipropylaMino)sulfonyl)-benzoicaci 4-(DipropylsulfaMoyl)benzoic acid 4-(dipropylsulfaMoyl)benzoicacid 4-[(dipropylaMino)sulfonyl]-benzoicaci Apurina benacen BeneMid beneMide Benuryl;Soluble probenecid;Probenecid 4-[(Dipropylamino)sulfonyl]benzoic acid;4-(Di-n-propylsulfamoyl)benzoesaeure
31 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • SynQuest Laboratories
  • Tocris
  • Usbiological
Package
  • p3000000
  • 1mg
  • 5mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 500mg
  • 1G
  • 2.5g
  • 5g
  • 10g
  • 50
  • 25g
  • 50g
  • 100g
  • 500g
  • ManufacturerAHH
  • Product numberMT-58157
  • Product descriptionProbenecid 98%
  • Packaging50g
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ53471
  • Product descriptionProbenecid
  • Packaging5g
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB20010
  • Product descriptionProbenecid, 98%
  • Packaging2.5g
  • Price$52.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003931
  • Product descriptionPROBENECID 95.00%
  • Packaging1G
  • Price$413
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003931
  • Product descriptionPROBENECID 95.00%
  • Packaging2.5G
  • Price$432.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBP166195
  • Product descriptionProbenecid
  • Packaging100mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14981
  • Product descriptionProbenecid ≥98%
  • Packaging5g
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26294
  • Product descriptionProbenecid
  • Packaging5mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14981
  • Product descriptionProbenecid ≥98%
  • Packaging10g
  • Price$48
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26294
  • Product descriptionProbenecid
  • Packaging25mg
  • Price$70
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14981
  • Product descriptionProbenecid ≥98%
  • Packaging25g
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14981
  • Product descriptionProbenecid ≥98%
  • Packaging100g
  • Price$305
  • Updated2024-03-01
  • Buy
  • ManufacturerChem-Impex
  • Product number38166
  • Product descriptionProbenecid,98%(Assaybytitration,HPLC) 98%(Assaybytitration,HPLC)
  • Packaging25G
  • Price$61.6
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number38166
  • Product descriptionProbenecid,98%(Assaybytitration,HPLC) 98%(Assaybytitration,HPLC)
  • Packaging100G
  • Price$202.72
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2646
  • Product descriptionProbenecid 99.78%
  • Packaging500mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2646
  • Product descriptionProbenecid 99.78%
  • Packaging1g
  • Price$60
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-58157 Probenecid 98% 50g $320 2021-12-16 Buy
AK Scientific J53471 Probenecid 5g $15 2021-12-16 Buy
Alfa Aesar B20010 Probenecid, 98% 2.5g $52.1 2021-12-16 Buy
American Custom Chemicals Corporation API0003931 PROBENECID 95.00% 1G $413 2021-12-16 Buy
American Custom Chemicals Corporation API0003931 PROBENECID 95.00% 2.5G $432.5 2021-12-16 Buy
Biosynth Carbosynth BP166195 Probenecid 100mg $50 2021-12-16 Buy
Cayman Chemical 14981 Probenecid ≥98% 5g $32 2024-03-01 Buy
Cayman Chemical 26294 Probenecid 5mg $32 2024-03-01 Buy
Cayman Chemical 14981 Probenecid ≥98% 10g $48 2024-03-01 Buy
Cayman Chemical 26294 Probenecid 25mg $70 2024-03-01 Buy
Cayman Chemical 14981 Probenecid ≥98% 25g $86 2024-03-01 Buy
Cayman Chemical 14981 Probenecid ≥98% 100g $305 2024-03-01 Buy
Chem-Impex 38166 Probenecid,98%(Assaybytitration,HPLC) 98%(Assaybytitration,HPLC) 25G $61.6 2021-12-16 Buy
Chem-Impex 38166 Probenecid,98%(Assaybytitration,HPLC) 98%(Assaybytitration,HPLC) 100G $202.72 2021-12-16 Buy
ChemScene CS-2646 Probenecid 99.78% 500mg $50 2021-12-16 Buy
ChemScene CS-2646 Probenecid 99.78% 1g $60 2021-12-16 Buy

Properties

Melting point :194-196°C
Boiling point :438.0±47.0 °C(Predicted)
Density :1.2483 (rough estimate)
refractive index :1.6800 (estimate)
storage temp. :Store at RT
solubility :DMSO (Slightly), Methanol (Slightly)
pka :5.8(at 25℃)
color :White to Off-White
Water Solubility :<0.1 g/100 mL at 20 ºC
Merck :14,7754
Stability :Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference :57-66-9(CAS DataBase Reference)
NIST Chemistry Reference :P-(dipropylsulfamoyl) benzoic acid(57-66-9)
EPA Substance Registry System :Probenecid (57-66-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Probenecid is a benzoic acid derivative that inhibits organic anion transporters (OATs) but activates the transient receptor potential (TRP) channel TRPV1. It inhibits OAT1, OAT3, and OAT6 with Ki values of 6.3, 9.0, and 8.4 μM, respectively, as well as OAT2 with an IC50 value of 0.67 μM. It is a poor inhibitor of the organic cation transporters OCT1 and OCT2 (IC50 = 1.6 and 1.7 mM, respectively). Through its effects on OATs, probenecid enhances the renal excretion of urate, alleviating gout, while reducing the elimination of many medications. It also acts as an agonist of TRPV2 (EC50 = 31.9 μM), eliciting nociceptive behavior under inflammatory conditions in mice.

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