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ChemicalBook >> CAS DataBase List >> Ravuconazole

Ravuconazole

Ravuconazole price.
  • $44 - $636
  • Product name: Ravuconazole
  • CAS: 182760-06-1
  • MF: C22H17F2N5OS
  • MW: 437.47
  • EINECS:
  • MDL Number:MFCD00941002
  • Synonyms:Aids057176;4-[2-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)b utan-2-yl]-1,3-thiazol-4-yl]benzonitrile;Aids-057176;Benzonitrile, 4-[2-[(1R,2R)-2-(2,4-difluro-phenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]-;Bms-207,147;Bms-207147;Er-30346;Rcz
16 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
Package
  • 1MG
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product numberX5181
  • Product descriptionRavuconazole
  • Packaging5mg
  • Price$163
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009900
  • Product descriptionRAVUCONAZOLE 95.00%
  • Packaging1MG
  • Price$367.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009900
  • Product descriptionRAVUCONAZOLE 95.00%
  • Packaging5MG
  • Price$496.89
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR157071
  • Product description[R-(R*,R*)]-4-{2-[2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)-propyl]-4-thiazolyl}-benzonitrile
  • Packaging5mg
  • Price$211
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR157071
  • Product description[R-(R*,R*)]-4-{2-[2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)-propyl]-4-thiazolyl}-benzonitrile
  • Packaging50mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18750
  • Product descriptionRavuconazole ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18750
  • Product descriptionRavuconazole ≥98%
  • Packaging5mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18750
  • Product descriptionRavuconazole ≥98%
  • Packaging10mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18750
  • Product descriptionRavuconazole ≥98%
  • Packaging25mg
  • Price$426
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6927
  • Product descriptionRavuconazole 99.63%
  • Packaging2mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6927
  • Product descriptionRavuconazole 99.63%
  • Packaging5mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6927
  • Product descriptionRavuconazole 99.63%
  • Packaging10mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6927
  • Product descriptionRavuconazole 99.63%
  • Packaging25mg
  • Price$354
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6927
  • Product descriptionRavuconazole 99.63%
  • Packaging50mg
  • Price$636
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1216
  • Product descriptionRavuconazole ≥97% (NMR)
  • Packaging5mg
  • Price$132
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1216
  • Product descriptionRavuconazole ≥97% (NMR)
  • Packaging25MG
  • Price$520
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X5181 Ravuconazole 5mg $163 2021-12-16 Buy
American Custom Chemicals Corporation API0009900 RAVUCONAZOLE 95.00% 1MG $367.5 2021-12-16 Buy
American Custom Chemicals Corporation API0009900 RAVUCONAZOLE 95.00% 5MG $496.89 2021-12-16 Buy
Biosynth Carbosynth FR157071 [R-(R*,R*)]-4-{2-[2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)-propyl]-4-thiazolyl}-benzonitrile 5mg $211 2021-12-16 Buy
Biosynth Carbosynth FR157071 [R-(R*,R*)]-4-{2-[2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)-propyl]-4-thiazolyl}-benzonitrile 50mg $600 2021-12-16 Buy
Cayman Chemical 18750 Ravuconazole ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 18750 Ravuconazole ≥98% 5mg $109 2024-03-01 Buy
Cayman Chemical 18750 Ravuconazole ≥98% 10mg $193 2024-03-01 Buy
Cayman Chemical 18750 Ravuconazole ≥98% 25mg $426 2024-03-01 Buy
ChemScene CS-6927 Ravuconazole 99.63% 2mg $60 2021-12-16 Buy
ChemScene CS-6927 Ravuconazole 99.63% 5mg $96 2021-12-16 Buy
ChemScene CS-6927 Ravuconazole 99.63% 10mg $168 2021-12-16 Buy
ChemScene CS-6927 Ravuconazole 99.63% 25mg $354 2021-12-16 Buy
ChemScene CS-6927 Ravuconazole 99.63% 50mg $636 2021-12-16 Buy
Sigma-Aldrich SML1216 Ravuconazole ≥97% (NMR) 5mg $132 2024-03-01 Buy
Sigma-Aldrich SML1216 Ravuconazole ≥97% (NMR) 25MG $520 2024-03-01 Buy

Properties

Melting point :64-66°C
alpha :D24 -29.1° (c = 1.03 in methanol)
Boiling point :674.9±65.0 °C(Predicted)
Density :1.38±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.25 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :11.62±0.29(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Ravuconazole is an orally available triazole fungicide that potently inhibits the growth of a wide range of fungi (MICs range from 25 to 780 ng/ml). Like other azoles, ravuconazole inhibits cytochrome P450 (CYP) isoforms that are involved in ergosterol biosynthesis, interfering with the generation of the fungal and protozoan cell membranes. Ravuconazole specifically inhibits sterol 14α-demethylase (CYP51). As this enzyme is also important in the development of trypanosomes, ravuconazole is effective against T. cruzi infections in animal models of Chagas disease.

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