Welcome to chemicalbook!
China English Japan Germany
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structured search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> TC ASK 10

TC ASK 10

TC ASK 10 price.
  • $32 - $1568
  • Product name: TC ASK 10
  • CAS: 1005775-56-3
  • MF: C21H22ClN5O
  • MW: 395.89
  • EINECS:
  • MDL Number:MFCD26792581
  • Synonyms:TC ASK 10;ASK1 Inhibitor 10;4-tert-butyl-N-(6-imidazol-1-ylimidazo[1,2-a]pyridin-2-yl)benzamide:hydrochloride;4-(1,1-Dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide dihydrochloride;Apoptosis,ASK1,oral,MAP3K,bioavailability,TC ASK-10,TC ASK10,Inhibitor,pharmacokinetic,JNK,TC ASK 10,p38,inhibit,selective,MAP kinase kinase kinase, MEKK, MAPKKK,Phosphorylation
Price21 Properties Safety Information Description
21 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Apolloscientific
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 5mg
  • 1mg
  • 50
  • 10mg
  • 2x10mg
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number7949DT
  • Product descriptionTCAsk10
  • Packaging10mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number7949DT
  • Product descriptionTCAsk10
  • Packaging25mg
  • Price$648
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5728
  • Product descriptionTCASK10
  • Packaging10mg
  • Price$385
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5728
  • Product descriptionTCASK10
  • Packaging50mg
  • Price$1568
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0302
  • Product descriptionTc ask 10
  • Packaging5mg
  • Price$169
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0302
  • Product descriptionTc ask 10
  • Packaging10mg
  • Price$270
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0302
  • Product descriptionTc ask 10
  • Packaging25mg
  • Price$568
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2179
  • Product descriptionASK1Inhibitor10 99%
  • Packaging10mg
  • Price$137.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2179
  • Product descriptionASK1Inhibitor10 99%
  • Packaging2x10mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number28512
  • Product descriptionASK1 Inhibitor 10
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28512
  • Product descriptionASK1 Inhibitor 10
  • Packaging5mg
  • Price$131
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28512
  • Product descriptionASK1 Inhibitor 10
  • Packaging10mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28512
  • Product descriptionASK1 Inhibitor 10
  • Packaging25mg
  • Price$494
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0026673
  • Product descriptionTCASK10 99.84%
  • Packaging5mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0026673
  • Product descriptionTCASK10 99.84%
  • Packaging10mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0026673
  • Product descriptionTCASK10 99.84%
  • Packaging25mg
  • Price$1060
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7949DT TCAsk10 10mg $336 2021-12-16 Buy
AK Scientific 7949DT TCAsk10 25mg $648 2021-12-16 Buy
ApexBio Technology B5728 TCASK10 10mg $385 2021-12-16 Buy
ApexBio Technology B5728 TCASK10 50mg $1568 2021-12-16 Buy
Apolloscientific BISN0302 Tc ask 10 5mg $169 2021-12-16 Buy
Apolloscientific BISN0302 Tc ask 10 10mg $270 2021-12-16 Buy
Apolloscientific BISN0302 Tc ask 10 25mg $568 2021-12-16 Buy
Axon Medchem Axon2179 ASK1Inhibitor10 99% 10mg $137.5 2021-12-16 Buy
Axon Medchem Axon2179 ASK1Inhibitor10 99% 2x10mg $220 2021-12-16 Buy
Cayman Chemical 28512 ASK1 Inhibitor 10 1mg $32 2024-03-01 Buy
Cayman Chemical 28512 ASK1 Inhibitor 10 5mg $131 2024-03-01 Buy
Cayman Chemical 28512 ASK1 Inhibitor 10 10mg $214 2024-03-01 Buy
Cayman Chemical 28512 ASK1 Inhibitor 10 25mg $494 2024-03-01 Buy
ChemScene CS-0026673 TCASK10 99.84% 5mg $350 2021-12-16 Buy
ChemScene CS-0026673 TCASK10 99.84% 10mg $550 2021-12-16 Buy
ChemScene CS-0026673 TCASK10 99.84% 25mg $1060 2021-12-16 Buy
Next Last

Properties

Melting point :>270° (dec.)
storage temp. :Refrigerator, under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ASK1 inhibitor 10 is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1; IC50 = 14 nM). It is selective for ASK1 over ASK2 (IC50 = 510 nM) as well as MEKK1, TAK-1, IKKβ, ERK1, JNK1, p38α, GSK3β, PKCθ, and B-RAF (IC50s = >10,000 nM for all). It inhibits streptozotocin-induced increases in JNK and p38 phosphorylation in INS-1 pancreatic β cells in a concentration-dependent manner.

Suppliers and manufacturers

TargetMol Chemicals Inc.
Career Henan Chemica Co
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Hangzhou MolCore BioPharmatech Co.,Ltd.
Aladdin Scientific ShangHai Caerulum Pharma Discovery Co., Ltd. EMMX Biotechnology LLC Shanghai EFE Biological Technology Co., Ltd. Beijing Jin Ming Biotechnology Co., Ltd. MQ (shanghai) Pharmaceuticals Co., Ltd.