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ChemicalBook >> CAS DataBase List >> Terbinafine Hydrochloride

Terbinafine Hydrochloride

Terbinafine Hydrochloride price.
  • $5 - $1050
  • Product name: Terbinafine Hydrochloride
  • CAS: 78628-80-5
  • MF: C21H26ClN
  • MW: 327.89
  • EINECS:616-640-4
  • MDL Number:MFCD00145430
  • Synonyms:Terbinafine hydrochloride, >=98%;Terbinafinehydrochloride(GMP);terbinafine hydrochloride, N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride;1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-, hydrochloride (1:1);Terbinafine Hydrochioride Tablets;n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamin(e)-1-naphthalenemethanaminmon ;TRANS-N-(6,6-DIMETHYL-2-HEPTEN-4-YNYL)-N-METHYL-1-NAPHTHYLMETHYLAMINE HYDROCHLORIDE;(e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamine monohydrochloride
44 prices
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Brand
  • Adipogen Life Sciences
  • AHH
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemcia Scientific
  • Chem-Impex
  • ChemScene
  • Chemtos
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
Package
  • 10mg
  • 25mg
  • 100mg
  • 200mg
  • 250mg
  • 0.500g
  • 1g
  • y0000535
  • 500mg
  • 5g
  • 250
  • 25g
  • 50
  • 10g
  • 10mM(in 1mL DMSO)
  • 100g
  • y0001143
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-T0207-G001
  • Product descriptionTerbinafine hydrochloride ≥98%(HPLC)
  • Packaging1g
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1217
  • Product descriptionTerbinafine hydrochloride 98%
  • Packaging25g
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2047
  • Product descriptionTerbinafineHCl
  • Packaging100mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2047
  • Product descriptionTerbinafineHCl
  • Packaging10mM(in 1mL DMSO)
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2047
  • Product descriptionTerbinafineHCl
  • Packaging200mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS039621
  • Product description(E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride ≥99%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS039621
  • Product description(E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride ≥99%
  • Packaging250mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS039621
  • Product description(E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride ≥99%
  • Packaging5g
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS039621
  • Product description(E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride ≥99%
  • Packaging10g
  • Price$18
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS039621
  • Product description(E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride ≥99%
  • Packaging25g
  • Price$24
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS039621
  • Product description(E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride ≥99%
  • Packaging100g
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1630
  • Product descriptionTerbinafine Hydrochloride
  • Packaging100mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1630
  • Product descriptionTerbinafine Hydrochloride
  • Packaging1g
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1630
  • Product descriptionTerbinafine Hydrochloride
  • Packaging10g
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546114
  • Product descriptionTerbinafine HCl >98%
  • Packaging100mg
  • Price$168.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546114
  • Product descriptionTerbinafine HCl >98%
  • Packaging500mg
  • Price$486.2
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-T0207-G001 Terbinafine hydrochloride ≥98%(HPLC) 1g $129 2021-12-16 Buy
AHH API-1217 Terbinafine hydrochloride 98% 25g $300 2021-12-16 Buy
ApexBio Technology B2047 TerbinafineHCl 100mg $50 2021-12-16 Buy
ApexBio Technology B2047 TerbinafineHCl 10mM(in 1mL DMSO) $80 2021-12-16 Buy
ApexBio Technology B2047 TerbinafineHCl 200mg $85 2021-12-16 Buy
Arctom AS039621 (E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride ≥99% 100mg $5 2021-12-16 Buy
Arctom AS039621 (E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride ≥99% 250mg $7 2021-12-16 Buy
Arctom AS039621 (E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride ≥99% 5g $10 2021-12-16 Buy
Arctom AS039621 (E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride ≥99% 10g $18 2021-12-16 Buy
Arctom AS039621 (E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride ≥99% 25g $24 2021-12-16 Buy
Arctom AS039621 (E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-aminehydrochloride ≥99% 100g $88 2021-12-16 Buy
AvaChem 1630 Terbinafine Hydrochloride 100mg $29 2021-12-16 Buy
AvaChem 1630 Terbinafine Hydrochloride 1g $35 2021-12-16 Buy
AvaChem 1630 Terbinafine Hydrochloride 10g $175 2021-12-16 Buy
Biorbyt Ltd orb546114 Terbinafine HCl >98% 100mg $168.3 2021-12-16 Buy
Biorbyt Ltd orb546114 Terbinafine HCl >98% 500mg $486.2 2021-12-16 Buy

Properties

Melting point :204-208°C
storage temp. :15-25°C
solubility :methanol: soluble50mg/mL
form :powder
color :white
Merck :14,9156
BCS Class :1
InChI :InChI=1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;
InChIKey :BWMISRWJRUSYEX-SZKNIZGXSA-N
SMILES :C12C=CC=CC1=CC=CC=2CN(C)C/C=C/C#CC(C)(C)C.Cl
CAS DataBase Reference :78628-80-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Terbinafine·HCl a member of the allylamine class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition. Squalene epoxidase is an enzyme released by the dermatophyte fungi to break down Squalene, which interferes with cell membrane function and wall synthesis. Research has shown that Terbinafine also reduces the ability of fungal pathogens to generate reactive oxygen species, therefore it is noted as a free radical scavenger in vitro and could potentially contain anti-inflammatory activity in vivo. Additionally, Terbinafine has also been reported to suppress cell proliferation in vitro and in vivo through inhibition of DNA synthesis and apoptosis activation. It has also been noted that by pretreating of cells with a p21 specific antisense oligonucleotide the Terbinafine induced inhibition of cell growth can be reversed. Assays further demonstrated that Terbinafine also contains anti-angiogenic effects in chick embryo chorioallantoic membranes. We provide this product in the hydrochloride form.

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