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ChemicalBook >> CAS DataBase List >> Udenafil

Udenafil

Udenafil price.
  • $90 - $1963.5
  • Product name: Udenafil
  • CAS: 268203-93-6
  • MF: C25H36N6O4S
  • MW: 516.66
  • EINECS:251-228-4
  • MDL Number:MFCD20275557
  • Synonyms:Benzenesulfonamide, 3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-D)pyrimidin-5-yl)-N-(2-(1-methyl-2-pyrrolidinyl)ethyl)-4-propoxy-;Da 8159;Da-8159;3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-(2-(1-methylpyrrolidin-2-yl)ethyl)-4-propoxybenzenesulfonamide;Udenafil;Udenafi;3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-propoxybenzenesulfonamide;5-[2-propyloxy-5-(2-(1-Methylpyrrolidin-2-yl)ethylaMinosulphonyl)phenyl]-1-Methyl-3-propyl-6,7-dihydro-1H-pyrazolo(4,3-d)pyriMidin-7-one
27 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10MG
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product number0257EM
  • Product descriptionUdenafil
  • Packaging250mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA444987
  • Product description3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-(2-(1-methylpyrrolidin-2-yl)ethyl)-4-propoxybenzenesulfonamide 98+%
  • Packaging100mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA444987
  • Product description3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-(2-(1-methylpyrrolidin-2-yl)ethyl)-4-propoxybenzenesulfonamide 98+%
  • Packaging250mg
  • Price$134
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA444987
  • Product description3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-(2-(1-methylpyrrolidin-2-yl)ethyl)-4-propoxybenzenesulfonamide 98+%
  • Packaging1g
  • Price$331
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008083
  • Product descriptionUDENAFIL 95.00%
  • Packaging10MG
  • Price$750.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008083
  • Product descriptionUDENAFIL 95.00%
  • Packaging100MG
  • Price$1963.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3439
  • Product descriptionUdenafil
  • Packaging5mg
  • Price$165
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146171
  • Product descriptionUdenafil >99%
  • Packaging100mg
  • Price$606.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146171
  • Product descriptionUdenafil >99%
  • Packaging250mg
  • Price$912.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146171
  • Product descriptionUdenafil >99%
  • Packaging1g
  • Price$1802
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFU28635
  • Product descriptionUdenafil
  • Packaging100mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFU28635
  • Product descriptionUdenafil
  • Packaging10mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFU28635
  • Product descriptionUdenafil
  • Packaging250mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFU28635
  • Product descriptionUdenafil
  • Packaging500mg
  • Price$325
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFU28635
  • Product descriptionUdenafil
  • Packaging50mg
  • Price$473
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number30373
  • Product descriptionUdenafil
  • Packaging5mg
  • Price$97
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0257EM Udenafil 250mg $320 2021-12-16 Buy
Ambeed A444987 3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-(2-(1-methylpyrrolidin-2-yl)ethyl)-4-propoxybenzenesulfonamide 98+% 100mg $90 2021-12-16 Buy
Ambeed A444987 3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-(2-(1-methylpyrrolidin-2-yl)ethyl)-4-propoxybenzenesulfonamide 98+% 250mg $134 2021-12-16 Buy
Ambeed A444987 3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-(2-(1-methylpyrrolidin-2-yl)ethyl)-4-propoxybenzenesulfonamide 98+% 1g $331 2021-12-16 Buy
American Custom Chemicals Corporation API0008083 UDENAFIL 95.00% 10MG $750.75 2021-12-16 Buy
American Custom Chemicals Corporation API0008083 UDENAFIL 95.00% 100MG $1963.5 2021-12-16 Buy
ApexBio Technology B3439 Udenafil 5mg $165 2021-12-16 Buy
Biorbyt Ltd orb146171 Udenafil >99% 100mg $606.9 2021-12-16 Buy
Biorbyt Ltd orb146171 Udenafil >99% 250mg $912.9 2021-12-16 Buy
Biorbyt Ltd orb146171 Udenafil >99% 1g $1802 2021-12-16 Buy
Biosynth Carbosynth FU28635 Udenafil 100mg $125 2021-12-16 Buy
Biosynth Carbosynth FU28635 Udenafil 10mg $135 2021-12-16 Buy
Biosynth Carbosynth FU28635 Udenafil 250mg $200 2021-12-16 Buy
Biosynth Carbosynth FU28635 Udenafil 500mg $325 2021-12-16 Buy
Biosynth Carbosynth FU28635 Udenafil 50mg $473 2021-12-16 Buy
Cayman Chemical 30373 Udenafil 5mg $97 2024-03-01 Buy

Properties

Melting point :152-159°C
Boiling point :697.0±65.0 °C(Predicted)
Density :1.35
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Chloroform (Slightly), Methanol (Sparingly)
form :Solid
pka :11.07±0.50(Predicted)
color :White to Pale Beige

Safety Information

Symbol(GHS):
Signal word:
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Description

Udenafil is the fourth in a class of drugs targeting the inhibition of the enzyme phosphodiesterase 5 (PDE5) for the treatment of erectile dysfunction. Inhibition of PDE5 results in the increase in endogenous cyclic guanosine monophosphate (cGMP) concentrations in the penile corpus cavernosum. cGMP induces smooth muscle cell relaxation and subsequent increased blood flow leading to a sustainable erection. Udenafil is a potent antagonist of human PDE5 with an IC50 of 8.25nM and a comparable selectivity profile as sildenafil for the other PDEs. Unlike tadalafil, it does not inhibit PDE11, which has been implicated in myalgia and testicular toxicity. Furthermore, udenafil produced up to a 91% vaginal penetration success rate and up to a 67% intercourse completion rate compared to a 29% completion rate by placebo. Overall patient satisfaction, measured by a standard global assessment question, was 86% compared to only 26% in the placebo group. The most frequently recorded adverse events were mild-to-moderate facial flushing and headache.

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