| | 51146-56-6 Basic information More.. |
| Product Name: | (S)-(+)-Ibuprofen | | Synonyms: | (S)-(+)-2-(4-ISOBUTYLPHENYL)PROPIONIC ACID;(S)-(+)-4-ISOBUTYL-ALPHA-METHYLPHENYLACETIC ACID;(S)-(+)-IBUPROFEN;(2s)-2-[4-(2-methylpropyl)phenyl]propionic acid;(S)-(+)-Ibuprofen ReagentPlus(R), 99%;(S)-2-(4-Isobutylphenyl)propanoic acid, 95+%;(S)-((addition))-Ibuprofen;(S)-(+)-4-Isobutyl-a-methylphenylacetic acid | | CAS: | 51146-56-6 | | MF: | C13H18O2 | | MW: | 206.28 | | EINECS: | 610-620-9 | | Mol File: | 51146-56-6.mol |  |
Use
Ibuprofen is a non-steroidal anti-inflammatory drug with diverse biochemical actions, most notably inhibiting COX-1 and COX-2 (IC50s = 2.6 and 1.53, μM, respectively). It is commonly synthesized as a racemic mixture of (S)- and (R)-isomers. (S)-Ibuprofen is an enantiomer that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form. (S)-Ibuprofen also inhibits activation of NF-κB more effectively than (R)-ibuprofen (IC50s = 62 and 122 μM, respectively). However, the enantiomers are equipotent in blocking superoxide formation, β-glucuronidase release, and LTB4 generation by stimulated neutrophils (IC50 values range from 0.14 to 0.58 μM). A majority of (R)-ibuprofen can be inverted to (S)-ibuprofen in humans after oral administration.
- (S)-(+)-Ibuprofen
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- US $0.00 / KG
- 2023-09-06
- CAS:51146-56-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
- (S) - (+) -Ibuprofen
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- US $5.70 / Kg/Bag
- 2023-03-06
- CAS:51146-56-6
- Min. Order: 10g
- Purity: 99%
- Supply Ability: 10000kg
- (S)-(+)-Ibuprofen
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- US $0.00 / Kg/Drum
- 2021-09-29
- CAS:51146-56-6
- Min. Order: 1KG
- Purity: 98.5%-101%
- Supply Ability: 1000kgs
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51146-56-6
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