61263-35-2 Basic information More..
Product Name:9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2
Synonyms:9-METHYLENE-11ALPHA,15R-DIHYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID;9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2;METENPROST;9-Deoxo-9-Methylene-16,16-diMethyl-PGE2;9-Deoxy-16,16-diMethyl-9-Methylene-PGF2;U 46785;5-heptenoicacid,7-(5,5-dimethyl-3-hydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl);7-(5,5-dimethyl-3-hydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)-5-heptenoicaci
CAS:61263-35-2
MF:C23H38O4
MW:378.55
EINECS:
Mol File:61263-35-2.mol
61263-35-2

Use

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 (PGE2; ) with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy. This prostaglandin mixture is ineffective on monkeys in their third trimester of pregnancy. Meteneprost, when compared to PGE2 and PGF1α, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems.

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