| | 175033-36-0 Basic information More.. |
| Product Name: | NO-ASPIRIN 1 | | Synonyms: | 2-(ACETYLOXY)-3-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID;NCX 4016;NO-ASPIRIN 1;2-AcetyloxybenzoicAcid3-NitrooxymethylphenylEster;nitroaspirin;3-(NitroxyMethyl)phenyl 2-acetoxybenzoate;2-Acetoxybenzoate-2-(1-nitroxymethyl)phenyl ester;C102148 | | CAS: | 175033-36-0 | | MF: | C16H13NO7 | | MW: | 331.28 | | EINECS: | | | Mol File: | 175033-36-0.mol |  |
Use
NO-Aspirin 1 is a hybrid molecule of aspirin and a nitric oxide (NO) donor. It contains an ester linkage, that when cleaved by esterases in the gut, liver, and plasma releases salicylate and an NO-releasing moiety. It also prevents restinosiis, inhibits proliferation of vascular smooth muscle cells, reduces infarct ssize following cardiac ischemia, and exhibits strong chemopreventative effects against colon cancer development.
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175033-36-0
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