107724-20-9 Basic information More..
Product Name:Eplerenone
Synonyms:(2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-diMethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate;HSDB 7522;Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo-, gamma-lactone, methyl ester, (7alpha,11alpha,17alpha)-;Eplerenone intermediate Eplerenone;(7α,11α,17α)-9,11-epoxy-17-hydroxy-3-oxo-γ-lactone-pregn-4-ene-7,21-dicarboxylic acid-7-methyl ester;Eplerenone for system suitability;Eplerenone for peak identification;EPLERENONE
CAS:107724-20-9
MF:C24H30O6
MW:414.49
EINECS:600-850-8
Mol File:107724-20-9.mol
107724-20-9

Use

Eplerenone derives its antihypertensive effect by blocking the binding of aldosterone at the mineralocorticoid receptor (mr). the drug, which was previously approved only for the oral treatment of hypertension, is now indicated to improve survival of stable patients with left ventricular systolic dysfunction (ejection fraction <40%) and clinical evidence congestive heart failure (chf) after an acute myocardial infarction.

Eplerenone manufacturers

  • Eplerenone
  • US $1.00 / g
  • 2024-05-16
  • CAS:107724-20-9
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 100kg
  • Eplerenone
  • US $301.00-250.00 / g
  • 2024-05-16
  • CAS:107724-20-9
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 8000g
  • Eplerenone
  • US $20.00-10.00 / kg
  • 2024-05-11
  • CAS:107724-20-9
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 20
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