17397-89-6 Basic information More..
Product Name:CERULENIN
Synonyms:CERULENIN FROM CEPHALOSPORIUM CAERULENS;[2R-[2.alpha.,3.alpha.(4E,7E)]]-3-(1-Oxo-4,7-nonadienyl)oxiranecarboxamide;2,3-EPOXY-4-OXO-7,10-DODECADIENAMIDE;(2R,3S,E,E)-2,3-EPOXY-4-OXO-7,10-DODECADIENAMIDE;2R,3S-EPOXY-4-OXO-7,10-DODECADIENAMIDE;[2R-[2alpha,3alpha(4E,7E)]]-3-(1-oxonona-4,7-dienyl)oxirane-2-carboxamide;2,3-epoxy-4-oxo-10-dodecadienamide;3-(1-oxo-4,7-nonadienyl)-,(2r-(2-alpha,3-alpha(4e,7e)))-oxiranecarboxamid
CAS:17397-89-6
MF:C12H17NO3
MW:223.27
EINECS:241-424-8
Mol File:17397-89-6.mol
17397-89-6

Use

Cerulenin is an epoxy fatty acid amide isolated from the fungus Cephalosporium caerulens identified as an antifungal in the 1960s. Over the past 40 years, cerulenin has found broad application in lipid biochemistry as an inhibitor fatty acid and sterol biosynthesis. Cerulenin binds to β-keto-acyl-ACP synthase blocking the interaction of malonyl CoA. Cerulenin also an inhibits bacterial fatty acid synthesis, acting on the FabH, FabB and FabF condensation enzymes. Cerulenin stimulates fatty acid oxidation and inhibits HMG-CoA synthetase activity.

CERULENIN manufacturers

  • CERULENIN USP/EP/BP
  • US $1.10 / g
  • 2021-06-25
  • CAS:17397-89-6
  • Min. Order: 1g
  • Purity: 99.9%
  • Supply Ability: 100 Tons Min
  • Cerulenin
  • US $1.00 / KG
  • 2020-05-10
  • CAS: 17397-89-6
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 20T
  • CERULENIN
  • US $1.00 / g
  • 2019-12-26
  • CAS:17397-89-6
  • Min. Order: 1g
  • Purity: ≥98%
  • Supply Ability: g/kg/Ton
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