| 1137868-52-0 Basic information More.. |
Product Name: | TAK-960 | Synonyms: | TAK-960;4-((9-Cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino)-2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)benzamide;4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)benzamide;CS-1725;TAK 960;TAK960;CS-554;Benzamide, 4-[(9-cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)-;Polo-like Kinase (PLK),cell,cancer,proliferation,Inhibitor,mitosis,TAK960,TAK 960,leukemia,inhibit,phosphorylation,lines,TAK-960 | CAS: | 1137868-52-0 | MF: | C27H34F3N7O3 | MW: | 561.6 | EINECS: | | Mol File: | 1137868-52-0.mol | |
Use
TAK-960 is a potent and selective inhibitor of polo-like kinase 1 (PLK1), a serine/threonine protein kinase involved in key processes during mitosis. TAK-960 has shown activity in several tumor cell l
ines, including those that express multidrug-resistant protein 1 (MDR1). TAK-960 treatments has shown significant efficacy against multiple tumor xenografts and is a potential chemotherapeutic agent f
or patients with advanced tumors.
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1137868-52-0
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NCE Biomedical Co.,Ltd.
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Product Name:TAK-960 CAS:1137868-52-0 Purity:99% HPLC Package:50Mg,100Mg,500Mg,1g,5g,10g,50g,100g,500g,1kg Remarks:XYA0106
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CB Index: |
55 |
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