Use
Matrine (MT) is a kind of alkaloid components found in the roots of Sophora species, having various pharmacological activities and are demonstrated to have anti-inflammatory, anti-allergic, anti-virus, antifibrotic, and cardiovascular protective effects. It is recently proved to have anti-cancer potentials, such as inhibiting cancer cell proliferation, inducing cell cycle arrest, accelerating apoptosis, restraining angiogenesis, inducing cell differentiation, inhibiting cancer metastasis and invasion, reversing multidrug resistance, and preventing or reducing chemotherapy- or radiotherapy-induced toxicity when combined with other chemotherapeutic drugs.