| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:Levuglandin E2;Levuglandin E-2,Levuglandin E2
CAS:91712-41-3
Purity:98% Package:5 mg
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| | (5Z,8R,9R,10E,12S)-8-acetyl-9-formyl-12-hydroxyheptadeca-5,10-dienoic acid Basic information |
| Product Name: | (5Z,8R,9R,10E,12S)-8-acetyl-9-formyl-12-hydroxyheptadeca-5,10-dienoic acid | | Synonyms: | (5Z,8R,9R,10E,12S)-8-acetyl-9-formyl-12-hydroxyheptadeca-5,10-dienoic acid;Levuglandin E2;(5Z,8R,9R,10E,12S)-8-Acetyl-12-hydroxy-9-formyl-5,10-heptadecadienoic acid;LGE2;levuglandin LGD2;Levuglandin E-2,Levuglandin E2 | | CAS: | 91712-41-3 | | MF: | C20H32O5 | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | 91712-41-3.mol |  |
| | (5Z,8R,9R,10E,12S)-8-acetyl-9-formyl-12-hydroxyheptadeca-5,10-dienoic acid Chemical Properties |
| | (5Z,8R,9R,10E,12S)-8-acetyl-9-formyl-12-hydroxyheptadeca-5,10-dienoic acid Usage And Synthesis |
| Description | Levuglandin E2 is a secoprostanoid from prostaglandin endoperoxide; gamma-ketoaldehyde cpd; related to prostaglandin E2. | | Definition | ChEBI: Levuglandin E2 is a levuglandin. | | in vitro | Levuglandin E2 (LGE2), a rearrangement product derived from the prostaglandin endoperoxide, PGH2, causes repair-resistant DNA-protein cross-links and cell death (LD50 = 230 nM) in V79 Chinese hamster lung fibroblasts._x000D_
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Reference: Biochemistry. 1993 Apr 20;32(15):4090-7. https://pubmed.ncbi.nlm.nih.gov/8471616/ | | in vivo | Treatment of LDL with LGE2 (Levuglandin E2) leads to uptake and degradation by mouse peritoneal macrophages. Oxidized LDL, but not acetyl LDL efficiently competed for binding and uptake of LGE2-modified 125I-LDL. This result suggests that LGE2-modified LDL was recognized by a class of scavenger receptor that demonstrated ligand specificity for oxidized LDL but not for acetyl LDL._x000D_
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Reference: Biochim Biophys Acta. 1997 Jan 7;1344(1):1-5. https://pubmed.ncbi.nlm.nih.gov/9022751/ | | target | Levuglandin E2 is a secoprostanoid from prostaglandin endoperoxide. |
| | (5Z,8R,9R,10E,12S)-8-acetyl-9-formyl-12-hydroxyheptadeca-5,10-dienoic acid Preparation Products And Raw materials |
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