| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
|
| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:QUIN 2-AM
CAS:83104-85-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
|
| Company Name: |
Beijing Ouhe Technology Co., Ltd
|
| Tel: |
010-82967028 13552068683 |
| Email: |
2355560935@qq.com |
| Products Intro: |
Product Name:QUIN 2-AM
CAS:83104-85-2
Purity:98% Package:1 mg Remarks:cas#83104-85-2
|
|
| | QUIN 2-AM Basic information |
| Product Name: | QUIN 2-AM | | Synonyms: | QUIN 2-AM;QUIN-2 TETRAACETOXYMETHYL ESTER;2-[(2-AMINO-5-METHYLPHENOXY)METHYL]-6-METHOXY-8-AMINO-QUINOLINE-N,N,N',N'-TETRAACETIC ACID TETRAKIS(ACETOXYMETHYL-ESTER);2-[[2-BIS(CARBOXYMETHYL)AMINO-5-METHYLPHENOXY]-METHYL]-6-METHOXY-8-BIS(CARBOXYMETHYL)AMINOQUINOLINE TETRAKIS(ACETOXYMETHYL) ESTER;quin2-acetoxymethylester;2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrakis(acetoxymethyl ester);2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,Nμ,Nμ-tetraacetic acid tetrakis(acetoxymethyl ester), 2-{[2-Bis(carboxymethyl)amino-5-methylphenoxy]-methyl}-6-methoxy-8-bis(carboxymethyl)aminoquinoline tetrakis(acetoxymethyl) ester;8-Amino-2-[(2-amino-5-methylphenoxy)-methyl]-6-methoxyquinoline-N,N,N',N'-tetraacetic acid | | CAS: | 83104-85-2 | | MF: | C38H43N3O18 | | MW: | 829.76 | | EINECS: | | | Product Categories: | Quinoline | | Mol File: | 83104-85-2.mol |  |
| | QUIN 2-AM Chemical Properties |
| density | 1.360 | | Fp | 113 °C | | storage temp. | −20°C | | solubility | DMSO: soluble | | form | A solid | | λmax | 348 nm | | Biological Applications | Calcium indicator |
| | QUIN 2-AM Usage And Synthesis |
| Description | Quin-2 AM is a cell-permeant acetoxymethyl ester of the high affinity fluorescent calcium indicator quin-2 . As quin-2 AM enters cells, it is hydrolyzed by intracellular esterases to produce quin-2. Quin-2 binds calcium with a Kd value of 115 nM. It displays high selectivity for calcium, as it is not affected by sodium gradients, membrane potential, or intracellular pH. High affinity probes like quin-2 are ideal for monitoring low levels of calcium, as are found in resting cells. Loadings of up to 2 mM quin-2 are without serious toxic effects, so quin-2 may be used to buffer intracellular calcium transients. Excitation and emission maxima for quin-2 are 339 and 492 nm, respectively. | | Uses | Fluorescent probe for measurement of calcium in biological systems and for selected divalent cations. | | Uses | 2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester) | | Uses | Quin 2-AM is a cell permeable fluorescent probe for Ca2+ that gives a large shift in the UV absorption spectrum and a 20-fold increase in fluorescence upon Ca2+ binding. |
| | QUIN 2-AM Preparation Products And Raw materials |
|