3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid

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Products Intro:	Product Name:3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid CAS:162401-62-9 Purity:0.99 Package:1KG;10KG Remarks:Gold product

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Products Intro:	Product Name:3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid CAS:162401-62-9 Purity:99% Package:100g ;1KG ;5KG 25KG

3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid manufacturers

3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid Basic information

Product Name:	3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid
Synonyms:	3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid;3-CyclopropyMethoxy-4-difluoroMethoxy benzoic acid;Benzoic acid, 3-(cyclopropylMethoxy)-4-(difluoroMethoxy)-;CYCLOPROPYL DIFLUOROMETHOXYBENOZOIC ACID;3-CyclopropylMethoxy-4-isopropoxy-benzoic acid;RofluMilast InterMediate II;3-Cyclopropylmethoxy-4-difluoromethoxybenzoic acid, >=98%;Roflumilast intermediate B
CAS:	162401-62-9
MF:	C12H12F2O4
MW:	258.22
EINECS:	605-288-7
Product Categories:	Roflumilast interemdiate;Intermediates
Mol File:	162401-62-9.mol

3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid Chemical Properties

Melting point	118-120℃
Boiling point	356.4±37.0 °C(Predicted)
density	1.355±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	3.87±0.10(Predicted)
color	White to Off-White
InChI	InChI=1S/C12H12F2O4/c13-12(14)18-9-4-3-8(11(15)16)5-10(9)17-6-7-1-2-7/h3-5,7,12H,1-2,6H2,(H,15,16)
InChIKey	IGFDIFLMMLWKKY-UHFFFAOYSA-N
SMILES	C(O)(=O)C1=CC=C(OC(F)F)C(OCC2CC2)=C1
CAS DataBase Reference	162401-62-9

Safety Information

MSDS Information

3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid Usage And Synthesis

Uses	An impurity and intermediate in the preparation of selective phosphodiesterase 4 (PDE4) inhibitor, Roflumilast (R639700).

3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid Preparation Products And Raw materials

Tag:3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid(162401-62-9) Related Product Information

Roflumilast benzaMide, N-(3,5-dichloro-4-pyridinyl)-4-(difluoroMethoxy)-3-hydroxy- BenzaMide, 3,4-bis(cyclopropylMethoxy)-N-(3,5-dichloro-4-pyridinyl)- 3-(cyclopropylMethoxy)-N-(3-(cyclopropylMethoxy)-4-(difluoroMethoxy)benzoyl)-N-(3,5-dichloropyridin-4-yl)-4-(difluoroMethoxy)benzaMide Roflumilast-d4 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast 4-Amino-3,5-dichloropyridine RofluMilast N-Oxide RofluMilast related substance Roflumilast N-(3-Chloropyridin-4-yl)-3-(cyclopropylMethoxy)-4-(difluoroMethoxy)benzaMide 4-Amino-3,5-dichloropyridine N-oxide RofluMilast related substance 3,5-DICHLORO-4-AMINOPYRIDINE Roflumilast N-oxide D4 3-CyclopropylMethoxy-4-Hydroxybenzaldehyde 4-(DIFLUOROMETHOXY)-3-(CYCLOPROPYLMETHOXY)-BENZALDEHYDE 3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE