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| | N-ACETYLTRYPTAMINE Basic information |
| Product Name: | N-ACETYLTRYPTAMINE | | Synonyms: | Acetotryptamide;N-[2-(1H-Indol-3-yl)-ethyl]-acetamide;3-(2-N-ACETYLAMINOETHYL)INDOLE;3-[2-(Acetylamino)ethyl]-1H-indole;N-Acetyl-1H-indole-3-ethaneamine;N-[2-(1H-indol-3-yl)ethyl]ethanamide;N-(2-(1H-Indol-3-yl);N-Acetyltryptamine | | CAS: | 1016-47-3 | | MF: | C12H14N2O | | MW: | 202.25 | | EINECS: | | | Product Categories: | | | Mol File: | 1016-47-3.mol |  |
| | N-ACETYLTRYPTAMINE Chemical Properties |
| Melting point | 74.0 to 78.0 °C | | Boiling point | 200°C/0.2mmHg(lit.) | | density | 1.164±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | alcohol: soluble | | form | powder | | pka | 16.48±0.46(Predicted) | | color | White to Light yellow to Light orange | | λmax | 290nm(MeOH)(lit.) | | CAS DataBase Reference | 1016-47-3 |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | HS Code | 2933.99.8290 |
| | N-ACETYLTRYPTAMINE Usage And Synthesis |
| Description | The Argentinian medicinal plant Prosopsis nigra contains this alkaloid of the simple
indole type which has recently been isolated and characterized. It may be a direct
precursor in the biosynthesis of the {:l-carboline bases. | | Description | N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; ) that binds the melatonin MT2 receptor (Ki = 41 nM). It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina. N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway. | | Uses | N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; ) that binds the melatonin MT2 receptor (Ki = 41 nM). It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina. N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway. | | Definition | ChEBI: A tryptamine compound having an acetyl substituent attached to the side-chain amino function. | | Enzyme inhibitor | This partial receptor agonist (FW = 202.26 g/mol; CAS 1016-47-3; Soluble to 100 mM in DMSO) is a melatonin (or 5-methoxy-N-acetyltryptamine) mimic and is more potent than melatonin in inhibiting dopamine release fom presynaptic melatonin receptor site of rabbit retina labeled in vitro with [3H]dopamine. | | storage | Room temperature | | References | Moro, Graziano, Coussio, Phytochern., 14,827 (1975) |
| | N-ACETYLTRYPTAMINE Preparation Products And Raw materials |
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