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Product Name: | ML162 | Synonyms: | 2-Chloro-N-(3-chloro-4-methoxyphenyl)-N-{2-oxo-2-[(2-phenylethyl)amino]-1-(2-thienyl)ethyl}acetamide;ML162;p62,Glutathione Peroxidase,GPX4,ML-162,Nrf2,anticancer,HRAS,Ferroptosis,Inhibitor,inhibit,ML 162,ML162;2-Thiopheneacetamide, α-[(2-chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-;2-Chloro-N-(3-chloro-4-methoxyphenyl)-N-(2-oxo-2-(phenethylamino)-1-(thiophen-2-yl)ethyl)acetamide | CAS: | 1035072-16-2 | MF: | C23H22Cl2N2O3S | MW: | 477.40338 | EINECS: | | Product Categories: | | Mol File: | 1035072-16-2.mol | ![ML162 Structure](CAS/20180713/GIF/1035072-16-2.gif) |
| ML162 Chemical Properties |
Boiling point | 699.3±55.0 °C(Predicted) | density | 1.342±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMF:10.0(Max Conc. mg/mL);20.95(Max Conc. mM) DMSO:25.0(Max Conc. mg/mL);52.37(Max Conc. mM) Ethanol:1.0(Max Conc. mg/mL);2.09(Max Conc. mM) | form | A crystalline solid | pka | 13.84±0.46(Predicted) |
| ML162 Usage And Synthesis |
Description | ML-162 is an inhibitor of glutathione peroxidase 4 (GPX4) and decreases GPX4 levels in MDA-MB-231 breast cancer cells, as well as the viability of BT-549 breast cancer cells. | storage | Store at -20°C |
| ML162 Preparation Products And Raw materials |
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