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S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O

S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Basic information
Product Name:S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O
Synonyms:(6S)-6-(diMethylaMino)-4,4-diphenylheptan-3-one;S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O;(s)-6-(dimethylamino)-4,4-diphenyl-3-heptanone;4-diphenyl-6-(dimethylamino)-(s)-3-heptanon;6s-methadone;d-6-(dimethylamino)-4,4-diphenyl-3-heptanone;dextromethadone;d-methadone
CAS:5653-80-5
MF:C21H27NO
MW:309.45
EINECS:
Product Categories:
Mol File:5653-80-5.mol
S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Structure
S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Chemical Properties
Melting point 100.5°C
Boiling point 449.71°C (rough estimate)
density 1.0350 (rough estimate)
refractive index 1.5614 (estimate)
solubility H2O: soluble
form solid
pka9.05±0.50(Predicted)
color white
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38-42/43
Safety Statements 22-26-36/37/39-45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS MJ6000000
ToxicityLD50 oral in mouse: 252mg/kg
MSDS Information
S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Usage And Synthesis
UsesDextromethadone-D3 is an impurity of Dextromethadone (CAS #: 5653-80-5). Dextromethadone is used in therapy for treating or preventing depression or other mood diseases.
DefinitionChEBI: Dextromethadone is a 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (S)-configuration. It is the less active enantiomer of methadone and has very little activity on opioid receptors and mainly responsible for the inhibition of hERG K+ channels and thus for cardiac toxicity. The drug is currently under clinical development for the treatment of major depressive disorder. It has a role as a NMDA receptor antagonist and an opioid analgesic. It is an enantiomer of a levomethadone.
S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O Preparation Products And Raw materials
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