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| Spiro[furo[2,3-f]-1,3-benzodioxole-7(6H),3'-[3H]indol]-2'(1'H)-one, 1'-[[5-(trifluoromethyl)-2-furanyl]methyl]-, (3'R)- Basic information |
Product Name: | Spiro[furo[2,3-f]-1,3-benzodioxole-7(6H),3'-[3H]indol]-2'(1'H)-one, 1'-[[5-(trifluoromethyl)-2-furanyl]methyl]-, (3'R)- | Synonyms: | Spiro[furo[2,3-f]-1,3-benzodioxole-7(6H),3'-[3H]indol]-2'(1'H)-one, 1'-[[5-(trifluoromethyl)-2-furanyl]methyl]-, (3'R)-;(R)-Funapide | CAS: | 1259933-15-7 | MF: | C22H14F3NO5 | MW: | 429.35 | EINECS: | | Product Categories: | | Mol File: | 1259933-15-7.mol | |
| Spiro[furo[2,3-f]-1,3-benzodioxole-7(6H),3'-[3H]indol]-2'(1'H)-one, 1'-[[5-(trifluoromethyl)-2-furanyl]methyl]-, (3'R)- Chemical Properties |
storage temp. | Store at -20°C | solubility | DMSO : 220 mg/mL (512.40 mM; Need ultrasonic) |
| Spiro[furo[2,3-f]-1,3-benzodioxole-7(6H),3'-[3H]indol]-2'(1'H)-one, 1'-[[5-(trifluoromethyl)-2-furanyl]methyl]-, (3'R)- Usage And Synthesis |
Biological Activity | (R)-Funapide ((R)-TV 45070) is the less active R-enantiomer of Funapide. Funapide is a potent Nav1.7 sodium channel blocker that can be used for pain research[1]. | References | [1]. Sharan K Bagal, et al. Recent progress in sodium channel modulators for pain. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9. |
| Spiro[furo[2,3-f]-1,3-benzodioxole-7(6H),3'-[3H]indol]-2'(1'H)-one, 1'-[[5-(trifluoromethyl)-2-furanyl]methyl]-, (3'R)- Preparation Products And Raw materials |
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