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N3-PEG3-tBu

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N3-PEG3-tBu Suppliers list
Company Name: 9i LLC
Tel: +18039569191
Email: MWan@NiNeiLab.com
Products Intro: Product Name:N3-PEG3-CH2CH2COOtBu
CAS:252881-73-5
Purity:min.95% Package:124USD/250 mg Remarks:NA638
Company Name: Chengdu Pukang Biotechnology Co., Ltd
Tel: 028-82550498
Email: export@pu-kang.com
Products Intro: Product Name:N3-PEG3-CH2CH2NH2
CAS:252881-73-5
Purity:98% Package:1g
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-61398051 +8613650506873
Email: sales@chemdad.com
Products Intro: Product Name:N3-PEG3-tBu
CAS:252881-73-5
Package:1kg，2kg，5kg，10kg，25kg
Company Name: SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tel: +86-021-61551413 +8618813727289
Email: contact@trustwe.com
Products Intro: Product Name:Azido-PEG3-t-butyl ester
CAS:252881-73-5
Purity:98% Package:Package as requetsed
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:N3-PEG3-CH2CH2-Boc
CAS:252881-73-5
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

N3-PEG3-tBu manufacturers
N3-PEG3-tBu Basic information
Product Name:N3-PEG3-tBu
Synonyms:N3-PEG3-CH2CH2COOtBu;N3-PEG3-tBu;N3-PEG3-CH2CH2COOtBu;3-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]propanoic acid 1,1-dimethylethyl ester;tert-butyl 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoate;Azido-PEG3-COOtBu;tert-Butyl 3-(2-(2-(2-azidoethoxyl)ethoxy)ethoxy)propanoate;N3-?PEG3-?t-?butyl ester
CAS:252881-73-5
MF:C13H25N3O5
MW:303.3547
EINECS:
Product Categories:SiChem;peg
Mol File:252881-73-5.mol
N3-PEG3-tBu Structure
N3-PEG3-tBu Chemical Properties
Safety Information
MSDS Information
N3-PEG3-tBu Usage And Synthesis
DescriptionAzido-PEG3-t-butyl ester is a click chemistry reagent. The hydrophilic PEG spacer increases solubility in aqueous media. The azide (N3) group canis reactive with alkyne, such as BCN, DBCO via Click Chemistry. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
UsesAzido-PEG3-t-butyl Ester is used as a linker in the conjugation of peptides.
Biological ActivityN3-PEG3-tBu is a cleavable ADC linker containing 3-unit PEG, which can be used to synthesize antibody drug conjugates (ADC). It is also a PROTAC linker, belonging to the PEG and Alkyl/ether classes, which can be used to synthesize PROTAC molecules.
in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

PEGs

Alkyl/ether

Cleavable

N3-PEG3-tBu Preparation Products And Raw materials
Preparation ProductsTERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA
Tag:N3-PEG3-tBu(252881-73-5) Related Product Information
Azido-dPEG4-acid alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol) Amino-PEG4-acid O-(2-AMINOETHYL)-O-(2-AZIDOETHYL)HEPTAETHYLENE GLYCOL 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL PEG-Azide, O-(2-Azidoethyl)-Oμ-methylpolyethylene glycol Z-9-aMino-4,7-dioxanonanoic acid 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine Amino-PEG6-alcohol O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) Azido-PEG12-azide N3-PEG4-tBu H2N-PEG8-tBu 3,6,9,12,15-PENTAOXAHEPTADECANE-1,17-DIYL BIS-AZIDE Amino-PEG8-azide AMINO-PEG12-T-BUTYL ESTER H2N-PEG6-tBu 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine