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CAS:140112-65-8
Package:10 mg;5 mg;50 mg Remarks: 90+%，具体纯度信息请见官网
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Product Name:Oleic Acid-2,6-diisopropylanilide
CAS:140112-65-8
Purity:98% Package:5mg;10mg;50mg
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Shanghai Hongye Biotechnology Co. Ltd
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Product Name:Oleic Acid-2,6-diisopropylanilide
CAS:140112-65-8
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Product Name:Oleic Acid-2,6-diisopropylanilide
CAS:140112-65-8
Purity:98% Package:10mg (solution); 50mg (solution); 5mg (solution) Remarks:Medbio
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Cayman Chemical Company
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Product Name:Oleic Acid-2,6-diisopropylanilide
CAS:140112-65-8
Package:>98% Remarks:10006782
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| | Oleic Acid-2,6-diisopropylanilide Basic information |
| | Oleic Acid-2,6-diisopropylanilide Chemical Properties |
| Boiling point | 557.7±49.0 °C(Predicted) | | density | 0.919±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml | | pka | 14.98±0.70(Predicted) |
| | Oleic Acid-2,6-diisopropylanilide Usage And Synthesis |
| Description | AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.1 Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol acyltransferase with an IC50 of 7 nM.2 When co-administered to rabbits or rats fed a high fat, high cholesterol diet, oleic acid-2,6-diisopropylanilide decreased low density lipoproteins and elevated high density lipoprotein levels when administered at 0.05%. | | References | 1. Suckling, K.E., and Stange, E.F. Role of acyl-CoA: Cholesterol acyltransferase in cellular cholesterol metabolism J. Lipid Res. 26(6),647-671(1985).
2. Roth, B.D., Blankley, C.J., Hoefle, M.L., et al. Inhibitors of acyl-CoA: Cholesterol acyltransferase. 1. Identification and structure-activity relationship of a novel series of fatty acid anilide hypocholesterolemic agents J. Med. Chem. 35(9),1609-1617(1992). |
| | Oleic Acid-2,6-diisopropylanilide Preparation Products And Raw materials |
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