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| | alisporivir Basic information |
| Product Name: | alisporivir | | Synonyms: | alisporivir;alisporivir /DB025/DB-025;Alisporivir (Debio-025);DEB-025;Debio-025;Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-D-alanyl-N-ethyl-L-valyl-L-valyl-N-methyl-L-leucyl] | | CAS: | 254435-95-5 | | MF: | C63H113N11O12 | | MW: | 1216.66 | | EINECS: | | | Product Categories: | | | Mol File: | 254435-95-5.mol |  |
| | alisporivir Chemical Properties |
| Boiling point | 1294.2±65.0 °C(Predicted) | | density | 1.011±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : ≥ 100 mg/mL (82.19 mM) | | pka | 13.32±0.70(Predicted) | | form | Solid | | color | White to off-white |
| | alisporivir Usage And Synthesis |
| Uses | Trofinetide is a synthetic analogue of the endogenous N-terminus tripeptide, Glycine-Proline-Glutamate (GPE), that has shown to be neuroprotective in animal models of brain injury. | | Definition | ChEBI: Alisporivir is a homodetic cyclic peptide. It has a role as an anticoronaviral agent. | | Biological Activity | Alisporivir is a Cyclophilin A inhibitor with potent anti-hepatitis C virus (HCV) activity. Alisporivir has also been investigated for Duchenne muscular dystrophy. | | in vivo | Combination treatment with Alisporivir and ICN-1229 does not protect against SARS-CoV infection in a mouse model[3]. |
| | alisporivir Preparation Products And Raw materials |
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