PNU-159682 manufacturers
- PNU-159682
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- $10.00 / 1mg
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2024-03-20
- CAS:202350-68-3
- Min. Order: 10mg
- Purity: 95%+
- Supply Ability: 500g
- PNU-159682
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- $7.00 / 1KG
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2020-02-14
- CAS: 202350-68-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100KG
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| | PNU-159682 Basic information |
| Product Name: | PNU-159682 | | Synonyms: | PNU-159682;PNU-159682 >95%;PNU-159682 95%;(8S,10S)-7,8,9,10-Tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[(1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy]-5,12-naphthacenedione;5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[(1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy]-, (8S,10S)-; 5-hydroxy-6-tert.-butyl-1,1-pentamethylene-3,3-dimethyl-indane;inhibit,non-Hodgkin’s lymphoma,PNU159682,ADCs Toxin,PNU-159682,acute myeloid leukemia,ADC Payload,EDV nanocell,AML,Inhibitor,ADC Cytotoxin,PNU 159682,Topoisomerase,NMS249,NHL;(8S,10S)-6,8,11-Trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-(((1S,3R,4aS,9S,9aR,10aS)-9-methoxy-1-methyloctahydro-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl)oxy)-7,8,9,10-tetrahydrotetracene-5,12-dione | | CAS: | 202350-68-3 | | MF: | C32H35NO13 | | MW: | 641.62 | | EINECS: | | | Product Categories: | | | Mol File: | 202350-68-3.mol |  |
| | PNU-159682 Chemical Properties |
| Boiling point | 838.5±65.0 °C(Predicted) | | density | 1.58±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 7.34±0.60(Predicted) |
| | PNU-159682 Usage And Synthesis |
| Characteristics | PNU-159682, a metabolite of the anthracycline neomycin metabolite, is a DNA topoisomerase I (TopoI) inhibitor with excellent cytotoxicity. It is a more potent and tolerable ADC cytotoxin than doxorubicin in ADC synthesis. | | Uses | PNU-159682 can be used in EDV nanocell technology to overcome drug resistance. |
| | PNU-159682 Preparation Products And Raw materials |
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