Log in | Join Free | china | japan | germany

2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide

Request For Quotation
2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:VUF 8430 dihydrobromide
CAS:100130-32-3
Package:10 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:VUF8430 dihydrobromide
CAS:100130-32-3
Purity:95% Package:$89.9/5mg;$159.9/10mg;$339.9/25mg;$579.9/50mg;Bulk package Remarks:95%
Company Name: EMMX Biotechnology LLC  
Tel: 888-539-0666
Email: info@emmx.com
Products Intro: Product Name:VUF 8430 dihydrobromide
CAS:100130-32-3
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
Company Name: Tianjin heowns Biochemical Technology Co., Ltd.  
Tel: 400-6387771-6039 18920564737
Email: sales@heowns.com
Products Intro: CAS:100130-32-3
Purity:98% Package:25mg 100mg 500mg 1g
Company Name: BOC Sciences  
Tel:
Email: info@bocsci.com
Products Intro: Product Name:VUF 8430 dihydrobromide
CAS:100130-32-3
Remarks:VUF 8430 dihydrobromide is a high affinity (pKi = 7.5) and potent histamine H4 receptor full agonist (pEC50 = 7.3). VUF 8430 also has moderate affinity for H3 receptors (pKi = 6.0) and weak partial ag
2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide Basic information
Product Name:2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide
Synonyms:2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide;2-[(Aminoiminomethyl)amino]ethyl carbamimidothioic acid ester;2-guanidinoethyl carbamimidothioate dihydrobromide;VUF 8430 dihydrobromide >=97% (NMR);VUF8430 hydrobromide;Carbamimidothioic acid, 2-[(aminoiminomethyl)amino]ethyl ester, dihydrobromide (9CI)
CAS:100130-32-3
MF:C4H13Br2N5S
MW:0
EINECS:
Product Categories:
Mol File:100130-32-3.mol
2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide Structure
2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide Chemical Properties
storage temp. room temp
solubility deionized water: soluble24mg/mL
form solid
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26
WGK Germany 3
RTECS UM6960000
MSDS Information
2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide Usage And Synthesis
DescriptionVUF8430 is a histamine H4 receptor agonist (Ki = 31.6 nM). It is selective for histamine H4 over H1 and H3 receptors in radioligand binding assays (Kis = >1 and 1 μM, respectively) and is less active in isolated guinea pig atria, which endogenously expresses high levels of H2 receptors (pD2 = 3.8). VUF8430 inhibits forskolin-induced, cAMP-mediated increases in β-galactosidase activity (EC50 = 50.1 nM). In vivo, VUF8430 (30 mg/kg) enhances HCl-induced formation of gastric lesions in rats. It also reduces mechanical and thermal allodynia in a mouse model of peripheral neuropathy induced by spared nerve injury (SNI).
UsesVUF 8430 Dihydrobromide is an H4 receptor agonist.
storageDesiccate at RT
2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide Preparation Products And Raw materials
Tag:2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide(100130-32-3) Related Product Information