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(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone

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(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone Basic information
Product Name:(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone
Synonyms:(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone;Gitingensine;Pregn-5-en-18-oic acid, 3-amino-20-hydroxy-, γ-lactone, (3α,20S)-
CAS:13084-70-3
MF:C21H31NO2
MW:329.48
EINECS:
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Mol File:13084-70-3.mol
(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone Structure
(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone Chemical Properties
Melting point 160°C
Safety Information
MSDS Information
(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone Usage And Synthesis
DescriptionGitingensine is a steroidal alkaloid which occurs in Kibatalia gitingensis, being found mainly in the leaves. It is optically active with a specific rotation of [α]31D - 65° (CHCI3). The hydrochloride has m.p. 281°C; [α]23D - 59.8° (CHCI3) and is more readily obtainable in the pure form than the free base. Deamination of the alkaloid by diazotization gives the deamino derivative, m.p. 235°C. The amino group may be methylated to yield the N-methyl compound, m.p. 223-4°C but the base cannot be methylated further.
DefinitionChEBI: Gitingensine is a steroid. It has a role as a metabolite.
ReferencesAnguilar-Santos, Philipp. J. Sci., 94, 217 (1965)
(20S)-3α-Amino-20-hydroxypregn-5-en-18-oic acid γ-lactone Preparation Products And Raw materials
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