(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN)
| 中文名称 | (GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN) |
|---|---|
| 中文同义词 | [CPP1-7,NPY19-23,ALA31,AIB32,GLN 34]-胰多肽;神经肽YY5受体激动剂多肽;(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21, ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN) TRIFLUOROACETATE SALT;神经肽GLY1,GLN4·16,THR6·13,TYR7,ASP10,ASN11,PRO14,ARG |
| 英文名称 | (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) |
| 英文同义词 | (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human);(Gly1,Gln4·16,Thr6·13,Tyr7,Asp10,Asn11,Pro14,Arg26,Met30,Ala31,Aib32)-Neuropeptide Y (huMan, rat);H-Gly-Pro-Ser-Gln-Pro-Thr-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Ala-Aib-Arg-Gln-Arg-Tyr-NH2;PubChem ID: 90479787;(Gly1,Ser3middot22,Gln4middot34,Thr6,Arg19,Tyr21,Ala23middot31,Aib32)-Pancreatic Polypeptide (human);Glycyl-L-prolyl-L-seryl-L-glutaminyl-L-prolyl-L-threonyl-L-tyrosyl-L-prolylglycyl-L-α-aspartyl-L-asparaginyl-L-alanyl-L-threonyl-L-prolyl-L-α-glutamyl-L-glutaminyl-L-methionyl-L-alanyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-seryl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-tyrosyl-L-isoleucyl-L-asparaginyl-L-methionyl-L-alanyl-2-methylalanyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosinamide;(Gly?,Ser?·??,Gln?·??,Thr?,Arg??,Tyr??,Ala??·??,Aib??)-Pancreatic Polypeptide (human) trifluoroacetate salt;Gly1,Gln4·16,Thr6·13,Tyr7,Asp10,Asn11,Pro14,Arg26 |
| CAS号 | 313988-89-5 |
| 分子式 | C183H281N57O54S2 |
| 分子量 | 4207.66874 |
| EINECS号 | |
| 相关类别 | 定制多肽;标准品 |
| Mol文件 | 313988-89-5.mol |
| 结构式 |  |
(GLY1,SER3·22,GLN4·34,THR6,ARG19,TYR21,ALA23·31,AIB32)-PANCREATIC POLYPEPTIDE (HUMAN) 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | 在 10% 乙腈中溶解度为 1 mg/ml |
| 形态 | 粉末 |
|
hY 5 receptor 0.24 nM (IC 50 ) |
hY 1 receptor 530 nM (IC 50 ) |
hY 2 receptor >500 nM (IC 50 ) |
hY 4 receptor 51 nM (IC 50 ) |
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide has IC 50 s of 530 nM, >500 nM, 51 nM for binding to the hY 1 , hY 4 , hY 2 receptors.
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide (0.2, 2 nmol/rat) induces a high amount of food intake in a dose-dependent manner in adult male rats weighing 340-400 g.