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L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-

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L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)- Suppliers list
Company Name: Suzhou Origin Specialty Chemicals Co., Ltd.
Tel: +86-512-68662322 +86-17312436797
Email: hanqun@origsc.com
Products Intro: Product Name:(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide
CAS:1948273-02-6
Purity:97%,ee 99% Package:100g;1KG;5KG
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:E3 ligase Ligand 1A
CAS:1948273-02-6
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: Jinan Carbotang Biotech Co.,Ltd.
Tel: +8615866703830
Email: figo.gao@foxmail.com
Products Intro: Product Name:L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-
CAS:1948273-02-6
Purity:98% Package:5KG;1KG
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:(S,R,S)-AHPC-Me
CAS:1948273-02-6
Package:1g Remarks:BOC Sciences also provides custom synthesis services for (S,R,S)-AHPC-Me.
Company Name: Zhengzhou Alfa Chemical Co.,Ltd
Tel: +8618530059196
Email: sale04@alfachem.cn
Products Intro: CAS:1948273-02-6
Purity:98% Package:5g; 25g; 100g; 500g; 1kg; 25kg
L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)- Basic information
Product Name:L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-
Synonyms:L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-;CPD101077;(S,R,S)-AHPC-Me;E3 ligase Ligand 1 (free base);(2S,4S)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-h ydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phen yl]ethyl]pyrrolidine-2-carboxamide;E3 ligase Ligand 1A;(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide;VHL ligand 2
CAS:1948273-02-6
MF:C23H32N4O3S
MW:444.59
EINECS:
Product Categories:
Mol File:1948273-02-6.mol
L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)- Structure
L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)- Chemical Properties
Boiling point 687.9±55.0 °C(Predicted)
density 1.233±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka14.00±0.40(Predicted)
InChIKeyJOSFQWNOUSNZBP-UUZHKXTQSA-N
SMILESC(N[C@H](C1=CC=C(C2SC=NC=2C)C=C1)C)(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@H](C(C)(C)C)N
Safety Information
MSDS Information
L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)- Usage And Synthesis
DescriptionE3 Ligase ligand 1a is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. E3 Ligase ligand 1a can be used to synthesize ARV-771, a BET PROTAC degrader.
Uses(4R)-3-Methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-L-prolinamide, is a ligand of E3 ligase,
L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)- Preparation Products And Raw materials
Tag:L-Prolinamide, 3-methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-, (4R)-(1948273-02-6) Related Product Information
E3 ligase Ligand 18 E3 ligase Ligand 10 E3 ligase Ligand 14 rac-((2R,3S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-hydroxy-4-phenylbutanoyl)-D-leucine Cereblon Ligand 1 4-Hydroxy ThalidoMide Protein degrader 1 (TFA) (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione