成骨生长肽
中文名称 | 成骨生长肽 |
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中文同义词 | 成骨生长肽;L-丙氨酰-L-亮氨酰-L-赖氨酰-L-精氨酰-L-谷氨酰甘氨酰-L-精氨酰-L-苏氨酰-L-亮氨酰-L-酪氨酰甘氨酰-L-苯丙氨酰甘氨酰-甘氨酸;醋酸成骨生长肽 |
英文名称 | OSTEOGENIC GROWTH PEPTIDE |
英文同义词 | Osteogenic Growth Peptide OGP;D-Alanyl-L-leucyl-L-lysyl-L-arginyl-L-glutaminylglycyl-L-arginyl-L-allothreonyl-L-leucyl-D-tyrosylglycyl-N-benzylglycylglycylglycinamide;Glycine, L-alanyl-L-leucyl-L-lysyl-L-arginyl-L-glutaminylglycyl-L-arginyl-L-threonyl-L-leucyl-L-tyrosylglycyl-L-phenylalanylglycyl-;OSTEOGENIC GROWTH PEPTIDE USP/EP/BP;OGP acetate |
CAS号 | 132996-61-3 |
分子式 | C68H110N22O18 |
分子量 | 1523.74 |
EINECS号 | |
相关类别 | 生化试剂-蛋白质;标准品;Peptide |
Mol文件 | 132996-61-3.mol |
结构式 |
成骨生长肽 性质
储存条件 | −20°C |
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形态 | 固体 |
颜色 | 白色至米白色 |
Osteogenic Growth Peptide (OGP) regulates proliferation, differentiation, and matrix mineralization in osteoblast lineage cells. The active portion of OGP, the OGP(10-14) region, is cleaved from the peptide and binds to the OGP receptor which activates the MAP kinase, the Src, and the RhoA pathways. Osteogenic Growth Peptide (OGP) is a native molecule with a primary structure identical to the C-terminus of histone H4, whose sequence contains a highly conserved 14-amino acid motif (NH 2 -ALKRQGRTLYGFGG-OH). This peptide is isolated from blood during osteogenic remodeling of post-ablation of marrow regeneration. The osteogenic growth peptide (OGP) and its C-terminal pentapeptide OGP(10-14) have been shown to stimulate the proliferation, differentiation, alkaline phosphatase activity and matrix mineralization of osteoblastic lineage cells.
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024/08/19 | HY-P1563 | 成骨生长肽 Osteogenic Growth Peptide, OGP | 132996-61-3 | 1mg | 950元 |
2024/08/19 | HY-P1563 | 成骨生长肽 Osteogenic Growth Peptide, OGP | 132996-61-3 | 5mg | 3900元 |