Company Name: |
TargetMol Chemicals Inc.
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Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:RAF mutant-IN-1;RAF mutant IN 1,RAF mutantIN1 CAS:2340020-82-6 Purity:98% Package:5 mg
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| RAF mutant-IN-1 Basic information |
| RAF mutant-IN-1 Chemical Properties |
storage temp. | Store at -20°C | solubility | Soluble in DMSO |
| RAF mutant-IN-1 Usage And Synthesis |
Description | RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1].
C-RAF 340D/Y341D|21 nM (IC50)|B-RafV600E|30 nM (IC50)|BRAFWT|392 nM (IC50)
| References | [1]. BAE, In Hwan, et al. Title of Invention: THIENO[3,2-d]PYRIMIDINE COMPOUND HA VING INHIBITORY ACTIVITY FOR PROTEIN KINASE. WO2019107987A1. |
| RAF mutant-IN-1 Preparation Products And Raw materials |
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