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| | setoclavine Basic information |
| Product Name: | setoclavine | | Synonyms: | setoclavine;9,10-Didehydro-6,8-dimethylergolin-8α-ol;Ergolin-8-ol, 9,10-didehydro-6,8-dimethyl-, (8α)- | | CAS: | 519-12-0 | | MF: | C16H18N2O | | MW: | 254.33 | | EINECS: | | | Product Categories: | | | Mol File: | 519-12-0.mol |  |
| | setoclavine Chemical Properties |
| Melting point | 216-222 °C (decomp)(Solv: ethyl ether (60-29-7)) | | Boiling point | 473.6±45.0 °C(Predicted) | | density | 1.30±0.1 g/cm3(Predicted) | | pka | 13.85±0.20(Predicted) |
| | setoclavine Usage And Synthesis |
| Description | An ergot alkaloid from the mycelia of Claviceps purpurea, the base yields colourless prisms when crystallized from Me2CO or MeOH. It is dextrorotatory having [α]20D + 165° (c 0.3, EtOH) or + 174° (c 1.0, CHCI3)' The ultraviolet spectrum in EtOH exhibits two absorption maxima at 243 and 313 mJ.1. The alkaloid forms crystalline salts with mineral acids, e.g. the hydrochloride, m.p. > 300°C and the nitrate, m.p. > 300°C;[α]20D + 190° (c 0.5,50% aqueous EtOH). The nitrogen atoms are present as an imino and a methylimino group. | | References | Hofmann et al., Helv. Chim. Acta, 40, 1358 (1957) |
| | setoclavine Preparation Products And Raw materials |
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